Results 51 to 60 of about 145,460,026 (308)

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

open access: yesMolecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou   +4 more
wiley   +1 more source

Replicating Processes: Testing the Project Points System at UNT Digital Projects [PDF]

open access: yes, 2017
Presentation at the 2017 Texas Conference on Digital Libraries. This presentation describes the replication of a points system used by Northwestern University's Digital Media Services department to better understand lab resources and capacity within the
Willis, Shannon, McIntosh, Marcia
core  

Digital curation bibliography: preservation and stewardship of scholarly works [PDF]

open access: yes, 2012
In a rapidly changing technological environment, the difficult task of ensuring long-term access to digital information is increasingly important. This publication presents over 650 English-language articles, books, and technical reports that are useful
Bailey, Charles   +3 more
core   +1 more source

La governamentalità algoritmica: radicalizzazione e strategia immunitaria del capitalismo e del neoliberalismo? [PDF]

open access: yesLa Deleuziana, 2016
This article is a set of reflections on the question: ‘what is completely new in algorithmic governmentality compared to capitalism and neoliberalism?’ The following text is thus some preliminary, temporary and definitively uncertain intuitions in ...
Antoinette Rouvroy
doaj  

The Digital as Digitality

open access: yes
Abstract When discussing the Middle East’s digital turn, it is essential to recognize inherent disjunctures between the predigital and the digital: between “old” media that clings to print publications, radio stations, and satellite television and “new” media that embraces and promotes the use of software, portals, social media, and ...
Mohamed Zayani, Joe F. Khalil
openaire   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

open access: yesMolecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic   +10 more
wiley   +1 more source

Digital Imaging Program fact sheet

open access: yes, 2004
Title from PDF caption (viewed May 11, 2007).; "January 2004."; Previously issued: Fact sheet / Digital Imaging Program. [Hartford] : State of Connecticut, Dept. of Social Services, [1996]
Digital Imaging Program (Conn.)
core   +1 more source

The Montreal Statement on Sustainability in the Digital Age

open access: yes, 2020
the Montreal Statement on Sustainability in the Digital Age is a collective statement from an international group of business, government, and science leaders highlights that we cannot achieve a climate-safe, sustainable, and equitable future without ...
Sustainability in the Digital Age
core   +1 more source

Greenstone: a comprehensive open-source digital library software system [PDF]

open access: yes, 2000
This paper describes the Greenstone digital library software, a comprehensive, open-source system for the construction and presentation of information collections.
Boddie, Stefan J.   +7 more
core   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

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