Results 31 to 40 of about 145,486,096 (258)
Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
Molecular Oncology, EarlyView.Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley +1 more source
Replicating Processes: Testing the Project Points System at UNT Digital Projects [PDF]
, 2017 Presentation at the 2017 Texas Conference on Digital Libraries. This presentation describes the replication of a points system used by Northwestern University's Digital Media Services department to better understand lab resources and capacity within the
Willis, Shannon, McIntosh, Marcia
core
Digital curation bibliography: preservation and stewardship of scholarly works [PDF]
, 2012 In a rapidly changing technological environment, the difficult task of ensuring long-term access to digital information is increasingly important. This publication presents over 650 English-language articles, books, and technical reports that are useful
Bailey, Charles +3 more
core +1 more source
Molecular Oncology, EarlyView.Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou +4 more
wiley +1 more source
La governamentalità algoritmica: radicalizzazione e strategia immunitaria del capitalismo e del neoliberalismo? [PDF]
La Deleuziana, 2016 This article is a set of reflections on the question: ‘what is completely new in algorithmic governmentality compared to capitalism and neoliberalism?’ The following text is thus some preliminary, temporary and definitively uncertain intuitions in ...
Antoinette Rouvroy
doaj
Errata to Sound Hashing Modes of Arbitrary Functions, Permutations, and Block Ciphers
IACR Transactions on Symmetric Cryptology, 2020 In ToSC 2018(4), Daemen et al. performed an in-depth investigation of sound hashing modes based on arbitrary functions, permutations, or block ciphers. However, for the case of invertible primitives, there is a glitch.
Aldo Gunsing, Joan Daemen, Bart Mennink
doaj +1 more source
Digital Imaging Program fact sheet
, 2004 Title from PDF caption (viewed May 11, 2007).; "January 2004."; Previously issued: Fact sheet / Digital Imaging Program. [Hartford] : State of Connecticut, Dept. of Social Services, [1996]
Digital Imaging Program (Conn.)
core +1 more source
The Montreal Statement on Sustainability in the Digital Age
, 2020 the Montreal Statement on Sustainability in the Digital Age is a collective statement from an international group of business, government, and science leaders highlights that we cannot achieve a climate-safe, sustainable, and equitable future without ...
Sustainability in the Digital Age
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Greenstone: a comprehensive open-source digital library software system [PDF]
, 2000 This paper describes the Greenstone digital library software, a comprehensive, open-source system for the construction and presentation of information collections.
Boddie, Stefan J. +7 more
core +1 more source