Results 31 to 40 of about 1,950,048 (268)

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

open access: yesFEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai   +4 more
wiley   +1 more source

Learning Indoor Environment for Effective LiFi Communications: Signal Detection and Resource Allocation

open access: yesIEEE Access, 2022
Seamless light fidelity (LiFi) communications in a realistic indoor environment faces a number of important challenges including the loss of line-of-sight (LOS) link due to the random orientation of mobile devices or blockage by users or furniture in the
Nurul Aini Amran   +3 more
doaj   +1 more source

Digital Technologies – Digital Culture [PDF]

open access: yesNordic Journal of Commercial Law, 2010
Nordic Journal of Commercial Law, No. 1 (2010)
openaire   +4 more sources

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

Souad BOUFISSIOU [PDF]

open access: yesAkofena
: Within the framework of the Algerian vision that emphasizes the importance of digital transformation in all sectors, including the health sector, the Algerian Ministry of Health intends to develop an integrated digital health system, through the ...
Analytical Sight on the Algerian Digital Health Strategy 2023-2027
doaj   +1 more source

Digital Collections and Digital Collecting Practices [PDF]

open access: yesProceedings of the 33rd Annual ACM Conference on Human Factors in Computing Systems, 2015
Reference is increasingly made to ‘digital collections’, yet this term encompasses accumulated digital objects of varying form, purpose and value. We review social science literature on mate-rial collections and draw from in-depth interviews with 20 peo-ple in the UK in order to offer a clearer understanding of what constitutes a digital collection and
Rebecca D. Watkins   +2 more
openaire   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

The Digital as Digitality

open access: yes
Abstract When discussing the Middle East’s digital turn, it is essential to recognize inherent disjunctures between the predigital and the digital: between “old” media that clings to print publications, radio stations, and satellite television and “new” media that embraces and promotes the use of software, portals, social media, and ...
Mohamed Zayani, Joe F. Khalil
openaire   +1 more source

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