Results 111 to 120 of about 18,256,021 (363)

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

open access: yesMolecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq   +8 more
wiley   +1 more source

The Son of Suda On-Line [PDF]

open access: yes, 2013
The Son of Suda On-Line (SoSOL) represents the first steps towards a collaborative, editorially-controlled, online editor for the Duke Databank of Documentary Papyri (DDbDP). Funded by the Andrew W.
team, Collaboration by Integrating Digital Papyrlogy
core  

Personal digital libraries: Keeping track of academic reading material

open access: yes, 2014
This paper discusses optionsfor tracking academic reading material and introduces a personal digital library solution. We combined and extended the open source projects Zotero and Greenstone such that material can be easily downloaded and ingested into ...
Sally Jo Cunningham   +9 more
core   +1 more source

Digital technologies: a new determinant of health

open access: yesThe Lancet: Digital Health, 2021
The Lancet Digital Health
doaj   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

Towards a digital library of popular music [PDF]

open access: yes, 1999
Digital libraries of music have the potential to capture popular imagination in ways that more scholarly libraries cannot. We are working towards a comprehensive digital library of musical material, including popular music.
Lloyd A. Smith   +9 more
core   +1 more source

Digital solutions for early breast cancer detection

open access: yesThe Lancet: Digital Health, 2023
The Lancet Digital Health
doaj   +1 more source

Digital humanities, digital methods, digital history, and digital outputs: History writing and the digital revolution [PDF]

open access: yesHistory Compass, 2018
Abstract While the term “digital humanities” appears inclusive, its exact meaning remains unclear and its early association with studies in English Literature means the term has already been partially superceded by “digital methods.” However, that renaming is problematic as it emphasises the research tools used while the field itself ...
openaire   +2 more sources

Why human connection is the true metric of research success

open access: yesFEBS Open Bio, EarlyView.
Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan   +3 more
wiley   +1 more source

The sky's the limit

open access: yesThe Lancet: Digital Health, 2022
The Lancet Digital Health
doaj   +1 more source

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