Results 51 to 60 of about 18,256,021 (363)
Understanding the Role of Digital Technologies in Education: A review
Sustainable Operations and Computers, 2022 One of the fundamental components of the United Nations’ sustainable development 2030 agenda is quality education. It aims to ensure inclusive and equitable quality education for all. Digital technologies have emerged as an essential tool to achieve this
Prof. Abid Haleem +3 more
semanticscholar +1 more source
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Family visits to libraries and bookshops: observations and implications for digital libraries
, 2014 This paper explores how families select books for leisure reading. We recruited 17 families (adults and children) for this study, and spent time with each in both bookshops and public libraries.
Sally Jo Cunningham +7 more
core +1 more source
Land, 2022 To accelerate the ecological civilization in the new era and coordinate the region’s ecological economic growth, land-use benefit pre-evaluations and coordination analyses must be carried out.
Daichao Li +4 more
doaj +1 more source
Molecular Oncology, EarlyView.Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
IEEE Access, 2022 Seamless light fidelity (LiFi) communications in a realistic indoor environment faces a number of important challenges including the loss of line-of-sight (LOS) link due to the random orientation of mobile devices or blockage by users or furniture in the
Nurul Aini Amran +3 more
doaj +1 more source
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Text mining in a digital library
, 2004 Digital librarians strive to add value to the collections they create and maintain. One way is through selectivity: a carefully chosen set of authoritative documents in a particular topic area is far more useful to those ...
Don, Katherine J. +7 more
core +1 more source
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source