Results 51 to 60 of about 9,213,396 (310)

From the Digitized to the Digital Library

open access: yesD-Lib Magazine, 2001
Historical Social Research.
openaire   +2 more sources

Digital curation and the cloud [PDF]

open access: yes, 2012
Digital curation involves a wide range of activities, many of which could benefit from cloud deployment to a greater or lesser extent. These range from infrequent, resource-intensive tasks which benefit from the ability to rapidly provision resources
Aitken, B.   +3 more
core  

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Algorithmic governmentality: radicalisation and immune strategy of capitalism and neoliberalism? [PDF]

open access: yesLa Deleuziana, 2016
This article is a set of reflections on the question: ‘what is completely new in algorithmic governmentality compared to capitalism and neoliberalism?’ The following text is thus some preliminary, temporary and definitively uncertain intuitions in ...
Antoinette Rouvroy
doaj  

Improving outpatient care for heart failure through digital innovation: a feasibility study

open access: yesPilot and Feasibility Studies, 2022
Background Heart failure (HF) affects over 26 million people worldwide. Multidisciplinary management strategies that include symptom monitoring and patient self-care support reduce HF hospitalization and mortality rates.
David O. Arnar   +10 more
doaj   +1 more source

Digital switchover and the role of the new BBC services in digital television take-up [PDF]

open access: yes, 2005
This paper discusses the process of digital switchover and assesses the role the BBC services have played in driving overall digital take-up and therefore bringing forward the likely date of analogue switch-off. The first part examines the advantages and
Iosifidis, P.
core   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Can technology increase COVID-19 vaccination rates?

open access: yesThe Lancet: Digital Health, 2021
The Lancet Digital Health
doaj   +1 more source

La gouvernementalité algorithmique : radicalisation et stratégie immunitaire du capitalisme et du néolibéralisme ? [PDF]

open access: yesLa Deleuziana, 2016
This article is a set of reflections on the question: ‘what is completely new in algorithmic governmentality compared to capitalism and neoliberalism?’ The following text is thus some preliminary, temporary and definitively uncertain intuitions in ...
Antoinette Rouvroy
doaj  

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