Results 41 to 50 of about 894,865 (310)

Bethlehem in the Bronze and Iron Ages in the light of recent discoveries by the Palestinian MOTA-DACH [PDF]

, 2015
The discovery of the necropolis of Khalet al-Jam’a, around 2.2 Km south-east of Bethlehem (Nigro et al. in this volume), provides new data on the Bronze and Iron Age town which controlled the main route connecting Jerusalem to Hebron, and the access to ...
Nigro, Lorenzo
core  

High Redshift Quasars and Star Formation in the Early Universe

, 2001
In order to derive information on the star formation history in the early universe we observed 6 high-redshift (z=3.4) quasars in the near-infrared to measure the relative iron and \mgii emission strengths.
Dietrich M., Dietrich M., Guilloteau S., Guilloteau S., I. Appenzeller, M. Dietrich, M. Vestergaard, Matteucci F., Perryman M. A. C., S. J. Wagner, Storey P. J., Taniguchi Y.   +11 more
core   +1 more source

PICALM::MLLT10 translocated leukemia

FEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen, Antonia C. Nakatsugawa, Natalie Barton, Henry Haines, Gary S. Stein, Janet L. Stein, Daniel S. Wechsler, Jessica L. Heath   +7 more
wiley   +1 more source

Between Bronze and Iron Ages (burial ground Shatmantamak I in Bashkortostan)

Поволжская археология, 2020
This study concerns the problem of diagnosing the materials of transitional period from the Bronze Age to the Early Iron Age on the territory of the Urals and Kazakhstan steppes.
Epimakhov Andrey V., Tairov Alexander D.   +1 more
doaj   +1 more source

New objects in old structures: The Iron Age hoard of the Palacio III megalithic funerary complex (Almadén de la Plata, Seville, Spain) [PDF]

, 2015
Cultural contact, exchange and interaction feature high in the list of challenging topics of current research on European Prehistory. Not far off is the issue of the changing role of monuments in the making and maintaining of key cultural devices such as
Forteza González, M, García Sanjuán, L, Hernández Arnedo, MJ, Hunt Ortiz, MA, Martinón-Torres, M, Murillo-Barroso, M, Wheatley, D   +6 more
core  

The Coming of Iron in a Comparative Perspective [PDF]

, 2016
The paper deals with the introduction of iron as a new raw material in the transition period between the outgoing Bronze Age and the Early Iron Age.
Bebermeier, Wiebke, Brumlich, Markolf, Cordani, Violetta, de Vincenzo, Salvatore, Eilbracht, Heidemarie, Klinger, Jörg, Knitter, Daniel, Lehnhardt, Enrico, Meyer, Michael, Schmid, Stephan G., Schütt, Brigitta, Thelemann, Michael, Wemhoff, Matthias   +12 more
core   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

Molecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié, Davod R. Shah, Eliane E. S. Brechbühl, Michael McNicholas, Zhaoyang Xu, John H. Stockley, Laura Morcom, Diana Gold Diaz, Gemma C. Girdler, Rachel V. Seear, Gabriel Balmus, Rajiv R. Ratan, Harry Bulstrode, James A. Nathan, Manav Pathania, Kevin M. Brindle, David H. Rowitch   +16 more
wiley   +1 more source

Reticulated Ceramics of Umilenie Settlement

Поволжская археология, 2021
The paper addresses the reticulated ceramics discovered in 1927 by V.I. Smirnov during the excavation of Umilenie settlement located in the vicinity of Lake Galichskoye.
Novikov Alexander V.
doaj   +1 more source

Z badań wykopaliskowych i inwentaryzacyjnych w Nowym Krakowie, gm. Darłowo, stan. 1 [PDF]

, 2018
The article presents history of hitherto conducing studies at this site. It is also aimed at presentation of a short-lived excavation of the early Roman Iron Age burial mound as well as the Hallstatt settlement features, conducted in the 1991 season.The ...
Skrzypek, Ignacy
core   +2 more sources

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source