Results 61 to 70 of about 299,168 (307)

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Alsace and Burgundy : Spatial Patterns in the Early Middle Ages, c. 600-900

Bulletin du Centre d’Études Médiévales d’Auxerre, 2018
This paper examines the long-term spatial concepts in today’s Northern Switzerland, in the north-east of Burgundy and in Alsace during Merovingian and Carolingian times (ca. 600-900).
Karl Weber
doaj   +1 more source

Hunting in the early Middle Ages [PDF]

, 2015
(in English): The thesis is devoted to hunting in Early Middle Ages in Czech Republic. The work summarizes the current knowledge of written sources and iconography.
Vaníčková Žemličková, Andrea
core  

Hominin footprints from Early Pleistocene deposits at Happisburgh, UK [PDF]

, 2014
The research was funded by the Calleva Foundation as part of the Pathways to Ancient Britain Project. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.Investigations at ...
Simon A. Parfitt, Hoare, Peter, Chris Stringer (67811), Williams Craig, Duffy, Sarah M., Simon A Parfitt, Lewis, M, Duffy, Sarah M, Peter Hoare, Peter Hoare (582679), De Groote, I, Parfitt, SA, Williams, Craig, Bates, M, Sarah M Duffy, Bates, R, Parfitt, Simon A, Isabelle De Groote, Martin Bates, Sarah M. Duffy (582676), Peglar, S, Duffy, SM, Ashton, N, Bates, Martin, Richard Bates (582678), Lewis, SG, Martin Bates (582677), Simon G Lewis, Chris Stringer, Lewis, Simon G, Parfitt, Simon A., Peglar, Sylvia, Isabelle De Groote (582675), Hoare Peter, Bates Richard, Williams, C, Sarah M. Duffy, Simon G. Lewis (582674), Simon G. Lewis, Stringer, C, Ashton, Nick, Mark Lewis, De Groote Isabelle, Duffy Sarah M., Hoare, P, Sylvia Peglar (582680), Craig Williams (582681), Ashton Nick, Sylvia Peglar, Stringer Chris, Stringer, Chris, Nick Ashton, Simon A. Parfitt (229984), Bates Martin, Bates, Richard, Bates, C. Richard, De Groote, Isabelle, Lewis Mark, Richard Bates, Parfitt Simon A., Nick Ashton (388306), Mark Lewis (393467), Lewis, Mark, Lewis, Simon G., Lewis Simon G., Peglar Sylvia, Craig Williams   +66 more
core   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Dreaming of the Middle Ages: the place of the 'mittelalterlich' and socialist awareness in Christina Stead's early fiction

, 2011
[Extract] The Middle Ages have proved to be imaginatively a fluid and artistically enticing entity. As Umberto Eco has underscored, many have turned to the Middle Ages for inspiration and diverse forms of confirmation (66-72).
Ackland, Michael
core  

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Book review: Bogachev A.V., Frantsuzov D.A. Costume of the Proto-Bulgars of the Middle Volga region: late 7th – early 10th century (Samara: SGTU, 2012, 350 pp.)

Поволжская археология, 2014
Methodological and source study aspects of the research devoted to the costume of early medieval cattle-breeding population of the Middle Volga region carried out in the monograph by A.V. Bogachev and D.A. Frantsuzov are examined in the review.
Liphanov Nikolay A.
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Craniology and odontology of the Early Medieval population alongside the Tobol river, based on Ustyug-1 burial ground

Вестник археологии, антропологии и этнографии, 2016
The article presents the results of craniological and odontological research based on a group of Ustyug-1 burial ground. The goal of the research is to determine genesis of the Bakal population from the Tobol river region of the Great Migration time ...
Poshekhonova O.E., Zubova A.V., Sleptsova A.V.   +2 more
doaj   +1 more source