Results 51 to 60 of about 127,902,927 (261)

Iron‐Tannic Acid Hydrogel Mediated Mild Photothermal Therapy Combined With Ferroptosis Enhances Anti‐Tumor Immunity in Colorectal Cancer

Advanced Science, EarlyView.
An injectable gelatin‐based tannic acid–iron hydrogel with mild photothermal therapy could not only induce immunogenic cell death, but also elicit ferroptosis of both tumor cells and tumor‐associated macrophages, resulting in DC maturation, T‐cell infiltration and down‐regulation of ferroptosis‐sensitive M2‐type TAMs levels.
Yuan Zhu, Xi Yu, Tao Wang, Wanyi Liu, Chang Lu, Jiani Zhong, Yujie He, Wei Li, Kunxi Zhang, Peihao Yin, Zeting Yuan   +10 more
wiley   +1 more source

China's Low‐Carbon Energy Transition Over the Past Two Decades: Experiences and Implications

Advanced Science, EarlyView.
China's low‐carbon energy transition features a brief decline and subsequent rebound in coal consumption, alongside the rapid expansion of renewable energy. This study develops a stage‐based analytical framework to explain this evolution from the perspectives of economic development, energy security, and environmental sustainability, revealing how ...
Yu Liu, Zhiyu Tian, Zhengxian Zhang, Xinbei Li   +3 more
wiley   +1 more source

A silent crisis: two decades of anaemia trends among women in the Eastern Mediterranean Region (2000–2019)

Archives of Medical Science
Introduction Anaemia remains a major public health issue. This condition adversely impacts women of reproductive age, especially in low-income countries. Although there is an ongoing global effort to reduce anaemia prevalence, progress is slow and uneven.
Reem Eltayeb, Ghaida Alsaif, Husam Qanash, Etaf Alshawarbeh, Naif K. Binsaleh   +4 more
doaj   +1 more source

GEOPOLITICAL PERSPECTIVE OF THE RUSSIAN FEDERATION AND BRZEZINSKI'S READINGS OF THE UKRAINIAN CRISIS [PDF]

Journal of Liberty and International Affairs, 2019
From November 2013 to the present day the Ukrainian crisis generated the most severe conflict in Europe since the 1990s, while current skirmishes in the eastern part of the country and recent new developments have the potential to further tighten the ...
Srdjan Orlandic
doaj  

The Cancer Cell Metabolic Reprogramming Remodels the Tumor Microenvironment: Molecular Mechanisms and Therapeutic Strategies

Advanced Science, EarlyView.
This review elucidates how cancer cell metabolic reprogramming—across glucose, lipid, amino acid, and nucleotide pathways—remodels the tumor microenvironment to suppress anti‐tumor immunity and promote immune escape. Targeting these metabolic axes offers promising strategies to overcome immunotherapy resistance and enhance cancer treatment.
Guoqing Xiang, Zhicheng Zhou, Xue Jiang, Zhenguang Du, Yangyang Zhan, Xinli Liu   +5 more
wiley   +1 more source

Do Retailers Compete Against Informal Firms? A Comparison of the Periods of the Global Crisis and Post-Crisis [PDF]

SocioEconomic Challenges
This study investigates the transformation of competitive dynamics between formal sector retailers and their informal sector counterparts in Eastern European and Central Asian countries after the 2008-2009 global financial crisis.
Ayse N. Balas, Halil D. Kaya
doaj   +1 more source

Constrained Forest Methane Sink by Thermal Adaptation of Soil Methanotrophs

Advanced Science, EarlyView.
Climate warming can stimulate methanotroph‐mediated CH4 oxidation in forest soils, thereby mitigating the increase in atmospheric CH4 concentrations. By integrating evidence from a macro‐climatic thermal gradient and a 70‐day incubation experiment, this study demonstrates that microbial methanotrophs can adapt to long‐term temperature changes at the ...
Baizhi Jiang, Xi Zhang, Zhenghu Zhou, Nianpeng He, Xuhui Zhou, Hongyang Chen   +5 more
wiley   +1 more source

AN ECOLOGICAL BACKGROUND OF THE DECLINE OF THE MIDDLE EASTERN CHRISTIANITY [PDF]

Вестник Православного Свято-Тихоновского гуманитарного университета: Серия I. Богословие, философия, 2007
In article is devoted to the decline of the Oriental Christianity in the Middle Ages inconnection with a seriuos ecological crisis of the Near Eastern region (degradation of vegeta-tion, soil erosion, expansion of the desert, nomadization ...
K. A. PANCHENKO
doaj  

The impact of the global economic and financial crisis on central, eastern and south-eastern Europe: A stock-taking exercise [PDF]

The paper first reviews the main drivers of the growth and real convergence process in central, eastern and south-eastern Europe (CESEE) since 2000 and assesses the key macro-financial strengths and vulnerabilities of the region at the beginning of the ...
Gardó, Sándor, Martin, Reiner
core  

A BSCB‐Penetrating Nanoplatform for Enhanced Luteolin Delivery in PRMT2‐Targeted Epigenetic Therapy of Spinal Cord Injury

Advanced Science, EarlyView.
In this work, MSN‐BO@LUT penetrates the blood‐spinal cord barrier for luteolin delivery in spinal cord injury. The nanodrug suppresses neuroinflammation and promotes functional recovery of the spinal cord. Mechanistically, luteolin targets protein arginine N‐methyltransferase (PRMT2) to decrease toll‐like receptor 4 (TLR4) methylation, thereby ...
Yixuan Wang, Bo Jin, Shipian Li, Qianxi Ouyang, Yu Xiao, Jiaxin Wen, Yehua Lai, Ping Wang, Yongjun Wang, Xuejun Cui, Weian Zhang, Min Yao   +11 more
wiley   +1 more source