Results 101 to 110 of about 1,470,470 (293)

ATG4B is required for mTORC1‐mediated anabolic activity and is associated with clinical outcomes in non‐small cell lung cancer

open access: yesFEBS Open Bio, EarlyView.
The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan   +6 more
wiley   +1 more source

A Bayesian vector error corrections model of the U.S. economy [PDF]

open access: yesWorking paper (Federal Reserve Bank of Philadelphia), 1998
This paper presents a small-scale macroeconometric time-series model that can be used to generate short-term forecasts for U.S. output, inflation, and the rate of unemployment. Drawing on both the Bayesian VAR and vector error corrections (VEC) literature, the author specifies the baseline model as a Bayesian VEC.
openaire   +3 more sources

Annotation Error Detection and Correction for Indonesian POS Tagging Corpus

open access: yesLontar Komputer
Linguistic Corpus is the primary material for training and evaluating machine learning models, especially for POS Tagging. However, the human-annotated corpus is not free from annotation errors.
Muhammad Alfian   +4 more
doaj   +1 more source

PREMIER - PRobabilistic Error-correction using Markov Inference in Errored Reads [PDF]

open access: yes, 2013
In this work we present a flexible, probabilistic and reference-free method of error correction for high throughput DNA sequencing data. The key is to exploit the high coverage of sequencing data and model short sequence outputs as independent ...
Dorman, Karin   +4 more
core   +3 more sources

Thresholds for Linear Optics Quantum Computing with Photon Loss at the Detectors

open access: yes, 2005
We calculate the error threshold for the linear optics quantum computing proposal by Knill, Laflamme and Milburn [Nature 409, pp. 46--52 (2001)] under an error model where photon detectors have efficiency
Christof Zalka   +5 more
core   +1 more source

Diabetes‐induced vascular calcification is associated with low pyrophosphate and its oral supplementation prevents calcification in diabetic mice

open access: yesFEBS Open Bio, EarlyView.
Induction of diabetes in three different mouse strains uniformly resulted in an increase in TNAP activity and a reduction in pyrophosphate (PPi) in the circulation. Inhibition of TNAP restored plasma PPi. Diabetes‐induced calcification in the media layer of the aorta was detected only in the Abcc6−/− strain, which is predisposed to ectopic ...
Krisztina Fülöp   +13 more
wiley   +1 more source

An Estimation of Residential Water Demand Using Co-Integration and Error Correction Techniques [PDF]

open access: yes
In this paper short- and long-run price elasticities of residential water demand are estimated using co-integration and error-correction methods. Unit root tests reveal that water use series and series of other variables affecting use are non-stationary.
Martinez-Espineira, Roberto
core   +1 more source

The Error Correction Model as a Test for Cointegration [PDF]

open access: yes, 2003
In this paper we generate critical values for a test for cointegration based on the joint significance of the levels terms in an error correction equation. We show that the appropriate critical values are higher than those derived from the standard F-distribution.
Athina Kanioura, Paul Turner
openaire   +2 more sources

SmallTalk: a novel small‐sized fusion tag for peptide expression and purification

open access: yesFEBS Open Bio, EarlyView.
The SmallTalk fusion tag allows for the efficient expression and purification of soluble recombinant proteins or peptides in Escherichia coli. Testing with SmallTalk‐GFP confirmed that the proteins were soluble and folded correctly, while SmallTalk‐Bin1b maintained its antimicrobial activity against various bacterial isolates. This streamlined workflow
Atika Tariq   +3 more
wiley   +1 more source

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