Results 81 to 90 of about 1,470,470 (293)
Molecular Oncology, EarlyView.Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz +15 more
wiley +1 more source
Approximate quantum error correction for generalized amplitude damping errors
, 2014 We present analytic estimates of the performances of various approximate quantum error correction schemes for the generalized amplitude damping (GAD) qubit channel. Specifically, we consider both stabilizer and nonadditive quantum codes.
Cafaro, Carlo, van Loock, Peter
core +1 more source
Molecular Oncology, EarlyView.The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués +3 more
wiley +1 more source
Research on grammatical error correction algorithm in English translation via deep learning
Journal of Intelligent SystemsThis study provides a concise overview of a grammatical error correction algorithm that is based on an encoder-decoder machine translation structure.
Cai Lihua
doaj +1 more source
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Decoherence by Correlated Noise and Quantum Error Correction
, 2005 We study the decoherence of a quantum computer in an environment which is inherently correlated in time and space. We first derive the nonunitary time evolution of the computer and environment in the presence of a stabilizer error correction code ...
A. Steane +6 more
core +1 more source
Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Molecular Oncology, EarlyView.Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source
Multi-parameter adjustment for high-precision azimuthal intersection positioning
MethodsX, 2020 The traditional azimuthal intersection method is viable for situations with only two control stations but a simple height averaging is not rigorous because the intersections vary in their distances from the two stations.
Songtao Ai +3 more
doaj +1 more source
Modeling the French Consumption Function Using SETAR Models [PDF]
We provide new estimations on aggregate consumption series in France using the framework of non-stationary threshold models. Most macroeconomists agree with the idea that, since the beginning of the seventies, the saving ratio has evolved irregularly ...
Gilles Dufrenot, Valerie Mignon
core
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source