Results 41 to 50 of about 21,707 (289)
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
International Review of Economics & FinanceExploring how Chinese manufacturing companies integrate digital technology to transform, upgrade, and enhance strategic risk management is essential in the digital economy age.
Zhongsheng Zhou, Jingyao Zhang, Chao He
doaj +1 more source
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Humanities & Social Sciences CommunicationsHealthcare managers and healthcare workers play a significant role in the provision of quality healthcare services. Unmet management expectations among healthcare workers lead to numerous problems.
Ayşegül Turan, Furkan Turan
doaj +1 more source
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
The Requirements of the Contemporary Labour Market for Professionals
Zeszyty Naukowe Szkoły Głównej Gospodarstwa Wiejskiego w Warszawie. Problemy Rolnictwa Światowego, 2018 The article substantiates that the contemporary labour market with its flexibility, volatility, high innovation dynamics, as its main features, introduces new requirements for employees.
Tetiana Balanovska, Barbara Wyrzykowska
doaj +1 more source
Remote managers are having trust issues
, 2020 Covid-19 has thrust many leaders into remote management which requires a different skill set than face-to-face management. They have been forced to make this transition quickly, and for the most part, without training.
Keller, Anita C. ; id_orcid +5 more
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FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
The expectation gap perceptions of internal audit managers by type of university attended in the Republic of South Africa [PDF]
, 2014 The development and rapid growth of the internal audit profession internationally, as well as the promulgation of new legislation in the RSA, combined with the assimilation of the King reports on governance into daily business life, has resulted in an ...
Fourie, Houdini, De Jager, Herman
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