Results 61 to 70 of about 2,244,036 (262)

Capacity Analysis of Distributed Antenna Systems with Multiple Receive Antennas over MIMO Fading Channel

International Journal of Antennas and Propagation, 2012
The downlink performance and capacity of distributed antenna systems (DASs) with multiple receive antennas are investigated in multi-input multi-output (MIMO) fading and multicell environment.
Xiangbin Yu, Xiaoshuai Liu, Yuyu Xin, Ming Chen, Yun Rui   +4 more
doaj   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

RESULTS OF DYNAMIC ASSESSMENT OF MELATONIN RECEPTOR EXPRESSION IN LYMPHOCYTES IN PATIENTS WITH ACUTE MILD AND SEVERE PANCREATITIS

Вестник хирургии имени И.И. Грекова, 2018
The authors present results of the investigation of melatonin receptors expression in lymphocytes in dynamics in 102 patients with acute pancreatitis of mild and severe form and in 50 volunteers. A correlated analysis was made between obtained results of
D. Yu. Semyonov, Z. H. Osmanov, A. G. Tonoyan, L. G. Shapkina, A. V. Sokolov, M. V. Gorchakova   +5 more
doaj   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

The effect of the acetyl-amide form of the synthetic peptide HLDF-6 on the CDH2 and CD24 expression in breast cancer

Сибирский научный медицинский журнал
The development and research of drugs capable of reducing the malignancy of tumors is one of the most promising areas in the differentiation therapy of breast cancer (BC).
S. A. Arkhipov, E. D. Mangazeeva, V. V. Arkhipova, A. P. Bogachuk, V. M. Lipkin, A. I. Autenshlyus   +5 more
doaj   +1 more source

Expression of CD44 on two lines of transplantable melanoma cells--relationship with cytokine secretion and tumor progression.

Folia Histochemica et Cytobiologica, 2004
In the present work it was investigated if a spontaneous alteration of the native melanotic transplantable melanoma form into amelanotic form, connected with the tumor progression, is accompanied by changes of CD44 surface glycoprotein expression.
Sławomir Wójcik, Małgorzata Zarzeczna, Mirosława Cichorek, Krystyna Kozłowska   +3 more
doaj   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source