Results 111 to 120 of about 136,580,157 (311)

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

THE IMPLEMENTATION OF THE STATE FAMILY POLICY IN MODERN RUSSIA

open access: yesВестник университета, 2017
Аnnotation: The smooth running of the modern family is impossible without implementation of the state family policy. Family policy is aimed not only to support individual families, but also to assist the social institution of the family is a vital ...
S. Kuzin, O. Kuchmaeva
doaj  

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Jolly family

open access: yes, 1878
This record was harvested from a previous catalogue system and will be withdrawn in 2025. Information in this record may be superseded or incomplete.
Armytage Family
core  

Family Medicine Forum

open access: yesCanadian Medical Education Journal, 2018
The College of Family Physicians of Canada
doaj   +1 more source

THE IMPLEMENTATION OF THE STATE FAMILY POLICY IN MODERN RUSSIA

open access: yesВестник университета, 2019
Аnnotation: The smooth running of the modern family is impossible without implementation of the state family policy. Family policy is aimed not only to support individual families, but also to assist the social institution of the family is a vital ...
S. Kuzin, O. Kuchmaeva
doaj  

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Genealogical Data from a Bryan Family Bible

open access: yes
The original manuscript is available in the Bryan Family Papers in the Special Collections Research Center, Swem Library, College of William and Mary.Includes genealogical data from a Bible owned by the Bryan ...
Bryan family
core  

Tuckwell family

open access: yes, 2022
This record was harvested from a previous catalogue system and will be withdrawn in 2025. Information in this record may be superseded or incomplete.
Armytage Family
core  

WhatsApp and YouTube as platforms for facilitating lifestyle modifications among individuals with hypertension in a low-income, urban community in Karachi, Pakistan: a qualitative study

open access: yesBMJ Public Health
Introduction Owing to an increase in internet access, mobile health is increasingly used to deliver health interventions in low- and middle-income countries.
Rashida A Ferrand   +6 more
doaj   +1 more source

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