Results 191 to 200 of about 13,568,970 (312)

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

open access: yesMolecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken   +7 more
wiley   +1 more source

Ethnic-Racial Identity and Alcohol Use Moderated by Family Factors among Diverse Emerging Adults. [PDF]

open access: yesRace Soc Probl
Walker CJ   +8 more
europepmc   +1 more source

Study with Family Members of Patients in the Intensive Care Unit: An Intervention of Medical Undergraduates

open access: diamond, 2017
Danielle Abdel Massih Pio   +5 more
openalex   +2 more sources

Genome-wide identification and expression specificity analysis of the DNA methyltransferase gene family under adversity stresses in cotton [PDF]

open access: gold, 2018
Xiaomin Yang   +11 more
openalex   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

Warm family of origin is associated with earlier disclosure of sexual abuse. [PDF]

open access: yesEur J Psychotraumatol
Barge C   +4 more
europepmc   +1 more source

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

open access: yesMolecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix   +13 more
wiley   +1 more source

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