Results 211 to 220 of about 149,865 (273)

Moss diatoms show regional structuring, high potential endemism, and an inverse latitudinal diversity gradient in the Arctic

Ecography, EarlyView.
Microorganisms perform essential functions in Arctic terrestrial ecosystems. Yet, their ecology and biogeography are poorly understood, despite being necessary to predict microbial responses to future climate change. Here, we provide the first large‐scale floristic and biogeographic study of the moss diatom flora in the tundra regions of the North ...
Charlotte Goeyers, Elie Verleyen, Bart Van de Vijver, Tyler J. Kohler, Petra Klímová, S. Robbert Gradstein, Koen Sabbe   +6 more
wiley   +1 more source

Severity of effect considerations regarding the use of mutation as a toxicological endpoint for risk assessment: A report from the 8th International Workshop on Genotoxicity Testing (IWGT)

Environmental and Molecular Mutagenesis, EarlyView.
Abstract Exposure levels without appreciable human health risk may be determined by dividing a point of departure on a dose–response curve (e.g., benchmark dose) by a composite adjustment factor (AF). An “effect severity” AF (ESAF) is employed in some regulatory contexts.
Barbara L. Parsons, Marc A. Beal, Kerry L. Dearfield, George R. Douglas, Min Gi, B. Bhaskar Gollapudi, Robert H. Heflich, Katsuyoshi Horibata, Michelle Kenyon, Alexandra S. Long, David P. Lovell, Anthony M. Lynch, Meagan B. Myers, Stefan Pfuhler, Alisa Vespa, Andreas Zeller, George E. Johnson, Paul A. White   +17 more
wiley   +1 more source

Remote Symptom Monitoring With Electronic Patient-Reported Outcomes in Clinical Cancer Populations.

JAMA Netw Open
Rocque GB, Franks JA, Deng L, Caston NE, Williams CP, Azuero A, Dent D, Jackson BE, McGowan C, Henderson NL, Huang CS, Ingram S, Odom JN, Eltoum N, Weiner B, Howell D, Stover AM, Pierce JY, Basch EM.   +18 more
europepmc   +1 more source

Relationship of Reduced Pain Intensity and Improved Quality-of-Life with Menstrual Migraine with Aspirin, Acetaminophen, and Caffeine Combination. [PDF]

Healthcare (Basel)
Mitra A, Araga M, Aher A, Xu J, Shanga G, Franks B, Petruschke R.   +6 more
europepmc   +1 more source

Evaluation of the standard battery of in vitro genotoxicity tests to predict in vivo genotoxicity through mathematical modeling: A report from the 8th International Workshop on Genotoxicity Testing

Environmental and Molecular Mutagenesis, EarlyView.
Abstract In human health risk assessment of chemicals and pharmaceuticals, identification of genotoxicity hazard usually starts with a standard battery of in vitro genotoxicity tests, which is needed to cover all genotoxicity endpoints. The individual tests included in the battery are not designed to pick up all endpoints.
Mirjam Luijten, Jan van Benthem, Takeshi Morita, Raffaella Corvi, Patricia A. Escobar, Yurika Fujita, Jennifer Hemmerich, Naveed Honarvar, David Kirkland, Naoki Koyama, David P. Lovell, Miriam Mathea, Andrew Williams, Stephen Dertinger, Stefan Pfuhler, Jeroen L. A. Pennings   +15 more
wiley   +1 more source

Policy Networks and Policy Entrepreneurship in the EU: Explaining Structural Policy Change in Pharmaceutical Innovation Incentives and Health Technology Assessment

European Policy Analysis, EarlyView.
ABSTRACT Policy process research has excelled in explaining structural policy change within national settings, but extensions and applications to the EU level have long proven challenging for scholars. Given that the EU is currently experiencing its longest period of Treaty stability since the 1980s—having evolved into a sui generis political system ...
Vassilis Karokis‐Mavrikos
wiley   +1 more source

Temporal constraints on leaf-level trait plasticity for next-generation land surface models. [PDF]

Ann Bot
Odé A, Smith NG, Rebel KT, de Boer HJ.
europepmc   +1 more source

Digital Rights Activism in Multilevel Governance

European Policy Analysis, EarlyView.
ABSTRACT Multilevel governance (MLG) without a clear hierarchical structure can create power imbalances among various actors, particularly in settings with overlapping jurisdictions and policy areas. This dynamic is especially pronounced in Internet governance, which faces a complex interplay of domestic laws, state interdependence, and heightened ...
Alison Harcourt
wiley   +1 more source

Looking back to look ahead: the temporal dimension of conservation seed bank collections. [PDF]

New Phytol
Mattana E, Godefroid S, Miles S, Carta A, Ensslin A, Chapman T, Viruel J.   +6 more
europepmc   +1 more source

Metabolic syndrome, accumulation of its components and risk of knee and hip replacement for osteoarthritis in community-dwelling older adults. [PDF]

Osteoarthr Cartil Open
Zeng M, Cicuttini FM, Franks A, McNeil JJ, Wang Y.   +4 more
europepmc   +1 more source