Results 171 to 180 of about 126,725,056 (277)

Stage‐Adaptive Janus Microneedle System for Redox‐Immune Regulation and Mitochondrial Protection in Infected Diabetic Wound Healing

Advanced Science, EarlyView.
ABSTRACT Infected diabetic wounds are sustained by a vicious cycle of hyperglycemia‐driven bacterial infection, persistent oxidative stress, and excessive inflammation, which collectively disrupt the ordered progression of tissue repair. Here, we engineered a stage‐adaptive Janus microneedle patch (MN‐FeSAC‐PPE) to enable a staged therapeutic process ...
Mengting Yin, Yu Zhang, Xinyu Qu, Jiayi Liu, Zhongyi Sun, Haibo Liu, Ziyan Chen, Jing Ru, Jingwen Han, Bingqiang Lu, Yan Lu, Yan Wang, Xinyu Zhao, Feng Chen   +13 more
wiley   +1 more source

Organoid Brain‐Machine‐Interface Devices for Central Nervous System Repair

Advanced Science, EarlyView.
We envision organoid brain‐machine‐interface (Organoid‐BMI) devices as new biohybrid bidirectional communication pathways to connect the human CNS and the external world for personalized CNS repair and regeneration. ABSTRACT Central nervous system (CNS) repair and regeneration suffer from tremendous clinical challenges due to current limitations in ...
Yantao Xing, Yang Yang, Zichen Hong, Chunhui Tian, Huiyu Chu, Susanne Clara Prokop, Hongwei Cai, Mingxia Gu, Jason Tchieu, Ken Mackie, Feng Guo   +10 more
wiley   +1 more source

Reply to Barbieri et al.: Out of the Land of Darkness: Plague on the fur trade routes. [PDF]

Proc Natl Acad Sci U S A, 2019
Bramanti B, Namouchi A, Schmid BV, Dean KR, Stenseth NC.   +4 more
europepmc   +1 more source

Genetic Variant c.245A>G (p.Asn82Ser) in GIPC3 Gene Is a Frequent Cause of Hereditary Nonsyndromic Sensorineural Hearing Loss in Chuvash Population. [PDF]

Genes (Basel), 2021
Petrova NV, Marakhonov AV, Balinova NV, Abrukova AV, Konovalov FA, Kutsev SI, Zinchenko RA.   +6 more
europepmc   +1 more source

Raman Evidence of Moiré Diamondene Formation by High‐Pressure

Advanced Science, EarlyView.
Two‐dimensional moiré diamondene is formed at approximately 2 GPa through the synergy of high pressure, interlayer twist, and a chemically active diamond (100) surface. It is a hybrid sp2–sp3 nanostructure, consists of localized nanodiamond domains and unbonded graphene segments.
Chaofeng Gao, Mingming Chang, Mengting Wang, Yu Chen, Shiyun Zheng, Jiankuan Wu, Min Chen, Keying Han, Luyuan Fan, Zhenxiao Zhang, Kun Zhai, Bochong Wang, Congpu Mu, Yingchun Cheng   +13 more
wiley   +1 more source

Biomimetic Gradient Hydrogels Regulate Osteochondral Regeneration Microenvironment Remodeling via Spatiotemporal Programming Engineering

Advanced Science, EarlyView.
Electric field‑driven continuous gradient hydrogel GHZF4 achieves spatiotemporal growth factor release, modulates immune microenvironment, angiogenesis and osteochondral differentiation. It realizes cell‑free functional osteochondral repair in rat/rabbit models, offering a promising biomimetic strategy for gradient tissue regeneration.
Xiaolian Niu, Shengzhao Xiao, Di Huang, Xuesong Wang, Yanwei Cao, Xiaodan Sun, Nicholas Dunne, Xiaoming Li   +7 more
wiley   +1 more source

Child health care system in Ukraine. [PDF]

Turk Pediatri Ars, 2020
Loboda A, Smiyan O, Popov S, Petrashenko V, Zaitsev I, Redko O, Zahorodnii M, Kasyan S.   +7 more
europepmc   +1 more source

A Novel IDO1/NE Dual Inhibitor, IMM‐H018 Prevents the Primary and Secondary Sepsis and Ameliorates the Kidney Injury Through Inhibiting the Cytokine Storm and Microthrombosis, and Reversing Immunosuppression

Advanced Science, EarlyView.
IMM‐H018, a dual IDO1/NE inhibitor, demonstrates potent therapeutic efficacy in sepsis by simultaneously targeting excessive inflammation and immune dysfunction. It prevents both primary and secondary sepsis through anti‐inflammatory, immune‐restoring, and renoprotective mechanisms, reducing organ damage, improving immune homeostasis, preserving kidney
Yi Zhou, Xiaodi Zhao, Xiaochen Pan, Zhiling Ma, Huaqing Cui, Hui Wen, Peng Wang, Xiufeng Liao, Kejie Qin, Yuchen Wang, Li Sheng, Sen Zhang   +11 more
wiley   +1 more source

Genetic Polymorphism of Y-Chromosome in Turkmen Population from Turkmenistan. [PDF]

Genes (Basel)
Zhabagin M, Tashkarayeva A, Bukayev A, Zhunussova A, Ponomarev G, Tayshanova S, Maxutova A, Adamov D, Balanovska E, Sabitov Z.   +9 more
europepmc   +1 more source