Results 181 to 190 of about 1,770,367 (305)

Engineered Bacteria Factory Integrating Drug Delivery and Antibody Manufacture for Activating the STING Signal Pathway Mediated Tumor Immunotherapy

Advanced Science, EarlyView.
To address the limitations of protein‐based ICIs in applications, this study constructed an engineered bacterium, HRB, capable of expressing aCD47 in hypoxic TME. Through the Schiff base reaction, responsive liposomes (LC) loaded with the STING agonist cGAMP were connected to the surface of bacteria to form HRB@LC.
Peng‐Shuo Dong, Tian Yao, Yong Li, Zi‐Hui Yan, Xiao‐Ting Xie, Jia‐Hua Zou, Kai Cheng, Jin‐Xuan Fan, Yuan‐Di Zhao, Qiu‐Ran Xu   +9 more
wiley   +1 more source

Scaling Up the Evidence: What Open Banking Brings to Gambling Research and Policy. [PDF]

J Gambl Stud
Murphy S, Muggleton N.
europepmc   +1 more source

Long‐Tea‐CLIP: An Expert‐Level Multimodal AI Framework for Fine‐Grained Green Tea Grading Across Five Sensory Dimensions

Advanced Science, EarlyView.
Long‐Tea‐CLIP (Contrastive Language‐Image Pre‐training) presents a multimodal AI framework that integrates visual, metabolomic, and sensory knowledge to grade green tea across appearance, soup color, aroma, taste, and infused leaf. By combining expert‐guided modeling with CLIP‐supervised learning, the system delivers fine‐grained quality evaluation and
Yanqun Xu, Zhengfang Xue, Qing Luo, Xu Liu, Yongquan Xu, Jing Huang, Xingcai Zhang, Xinyuan Zhang, Zhonghua Liu, Zisheng Luo   +9 more
wiley   +1 more source

Nurses and Midwives Mistakes and Errors in Pediatric Health Outcomes in Southwestern Uganda. [PDF]

Pediatric Health Med Ther
Akantorana M, Tumwesigye R, Nalwanga CM, Niyonzima V, Luwaga R, Beebwa E.   +5 more
europepmc   +1 more source

Knitted Pneumatic Fabrics for Dynamic Pressure Modulation in Personalized Healthcare Wearables

Advanced Science, EarlyView.
A pneumatic pressure‐regulating knitted fabric (PPKF) is developed, in which knitted pneumatic circuit enables the seamless integration of ultralow radial expansion pneumatic fiber into dual‐channel textile structure. By strategically modulating channel spacing, delivering adjustable dynamic pressures and clinically relevant gradient compression ratios.
Xiaoyu Chen, Jintu Fan, Rong Zheng, Qing Chen, Fengxin Sun, Huanhuan Liu   +5 more
wiley   +1 more source

Commodity risk assessment of <i>Lonicera ligustrina</i> var. <i>pileata</i>, <i>Lonicera ligustrina</i> var. <i>yunnanensis</i> and <i>Lonicera periclymenum</i> plants from the UK. [PDF]

EFSA J
EFSA Panel on Plant Health (PLH), Vicent Civera A, Baptista P, Berlin A, Chatzivassiliou E, Cubero J, Cunniffe N, de la Peña E, Desneux N, Di Serio F, Filipiak A, Gonthier P, Hasiów-Jaroszewska B, Jactel H, Landa BB, Maistrello L, Makowski D, Milonas P, Papadopoulos NT, Susi H, van der Gaag DJ, Debode J, Navas-Cortes JA, Kritikos C, Kormpi M, Papachristos D, Reppa C, Akrivou A, Antonatos S, Beris D, Schulz OM, Lombardo MF, Gardi C, Potting R.   +33 more
europepmc   +1 more source

Nicotinamide and Pyridoxine Supplementation Enhances Muscle Stem Cell Activity and Muscle Regeneration in Humans: A Randomized Placebo‐Controlled Clinical Trial of High Force Eccentric Contraction Recovery in Healthy Young Men

Advanced Science, EarlyView.
In a randomized clinical trial, we test the potential of combined nicotinamide (NAM) and pyridoxine (PN) to improve muscle recovery through muscle stem cell (MuSC) activity. Daily oral NAM and PN supplementation after high intensity muscle contractions enhances MuSC activation and differentiation, and accelerates muscle regeneration, providing new ...
Grith Højfeldt, Joris Michaud, Ann Damgaard, Karoline Karlog, Eugenia Migliavacca, Sonia Karaz, Elham Pazirandeh‐Micol, Odd E. Johansen, Leonidas G. Karagounis, Bjørk W. Helge, William Hagemann, Michael Kjaer, Jerome N. Feige, Pascal Stuelsatz, Abigail L. Mackey   +14 more
wiley   +1 more source

Political appeals in tobacco marketing: Tucker Carlson unveils Alp nicotine pouch brand on X. [PDF]

Tob Control
Kostygina G, Carter CC, Barari S, Borowiecki M, Emery SL.   +4 more
europepmc   +1 more source

Context‐Dependent Role of GDF15: GDF15+ Tumor‐Associated Macrophages Suppress OSCC Progression by Enhancing Phagocytosis

Advanced Science, EarlyView.
This study identifies GDF15+ TAMs as a cell subset mediating tumor regression after immunotherapy. Macrophage‐intrinsic GDF15 enhances phagocytosis and antigen cross‐presentation to CD8+ T cells through the NF‐κB signaling pathway, thereby inhibiting tumor progression.
Xinyu Zhou, Zhihang Zhou, Houyu Ju, Chaoyang Guo, Fangxing Zhu, Yiyi Zhang, Xu Chen, Tongchao Zhao, Laiping Zhong, Jingzhou Hu   +9 more
wiley   +1 more source

Environmental impact of computer-aided diagnosis in colonoscopy: a carbon footprint assessment of a prospective study cohort. [PDF]

Endoscopy
Olabintan O, Halvorsen N, Baddeley R, Kudo SE, Barua I, Misawa M, Mori K, Hunt C, Nilsen JA, Frigstad SO, East JE, Rastogi A, Hassan C, Kalager M, Løberg M, Haji A, Holme Ø, Bretthauer M, Hayee B, Mori Y, Gulati S.   +20 more
europepmc   +1 more source