Results 101 to 110 of about 127,114,064 (323)
Eaten alive: a history of macroautophagy
Macroautophagy (hereafter autophagy), or 'self-eating', is a conserved cellular pathway that controls protein and organelle degradation, and has essential roles in survival, development and homeostasis.
Zhifen Yang, D. Klionsky
semanticscholar +1 more source
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
Duration of Menopausal Vasomotor Symptoms Over the Menopause Transition
IMPORTANCE The expected duration of menopausal vasomotor symptoms (VMS) is important to women making decisions about possible treatments. OBJECTIVES To determine total duration of frequent VMS (≥6 days in the previous 2 weeks) (hereafter total VMS ...
N. Avis +10 more
semanticscholar +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
¿Sin Dolores? La ética política de Maquiavelo y Weber en The Sweet Hereafter
This article, on one hand, seeks to analyze the relationship between ethics and politics through Atom Egoyan's film, The Sweet Hereafter ; and on the other hand, it means to demonstrate that theoretical reflection on certain questions not only can and ...
Javier Franzé
doaj
Modelling stem cell differentiation related processes—A practical overview for biologists
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Design and analysis strategies for robust microbiome ageing research
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Belief in the hereafter in the Nusayri sect
Hz. Peygamber'in vefatının ardından mezhepsel oluşumlar ortaya çıkmıştır. Bunlar arasında yer bulan Nusayri mezhebi, Muhammed b. Nusayr en- Nemiri tarafından kurulan, Hamdan el- Hasibî tarafından sistematik hale getirilen Şiî Bâtıni bir fırka olarak
Seyit, Büşra Meryem
core
“Safeguarding the Right to Data Protection in the EU”, 30th and 31st October 2014, Paris, France
This contribution is based on presentations and discussions at the conference “Safeguarding the Right to Data Protection”, held in Paris on the 30th and 31st October, 2014.
Mistale Taylor
doaj +1 more source

