Results 151 to 160 of about 461,298 (339)
The existence of hereafter in Wahiduddin Khan
Kelam ilminin tarihi açıdan geçirdiği üç dönemden biri yeni ilm-i kelam dönemidir. 19. ve 20. yüzyıldaki bilimsel gelişmeler din-bilim arasında birtakım çatışmaların patlak vermesine ve dinî ilimlerin yeniden yorumlanması ihtiyacına zemin hazırlamıştır ...
Çalışkan, Yusuf
core
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
Molecular Oncology, EarlyView.Circulating tumor cells (CTCs) and plasma cell‐free DNA (cfDNA) were analyzed to detect ESR1 mutations and methylation in patients with advanced breast cancer. CTC‐derived DNA showed higher sensitivity for mutation detection and revealed complementary genetic and epigenetic alterations, highlighting the added value of CTC analysis for understanding ...
Dimitra Stergiopoulou +12 more
wiley +1 more source
, 2013 In the course of reflecting on Tom Greggs' recent claim that Barth ‘did not reject universalism [...] only problematic elements associated with it’, Mark Koonz raises the fascinating question of Barth’s doctrinal position on universalism.
Koonz, Mark
core +1 more source
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
Molecular Oncology, EarlyView.Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen +14 more
wiley +1 more source
Permanent scatterers in SAR interferometry
IEEE 1999 International Geoscience and Remote Sensing Symposium. IGARSS'99 (Cat. No.99CH36293), 1999 A. Ferretti, C. Prati, F. Rocca
semanticscholar +1 more source
Molecular Oncology, EarlyView.A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel +12 more
wiley +1 more source
Psychosocial Factors Associated with Help-Seeking Intention Among Adults in Rural Japan. [PDF]
Yonago Acta MedTakeda S +12 more
europepmc +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source