Results 91 to 100 of about 126,975,673 (286)
Mathematics, 2018 Orthogonal projection a point onto a parametric curve, three classic first order algorithms have been presented by Hartmann (1999), Hoschek, et al. (1993) and Hu, et al. (2000) (hereafter, H-H-H method). In this research, we give a proof of the approach&#
Juan Liang +5 more
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Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
FEBS Letters, EarlyView.Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
LiteratureIn his poem The Rape of Lucrece, Shakespeare uses ekphrasis—the virtuosic description of a piece of art such as a painting, tapestry, or tableau—to critique the Roman ideal of female virtue.
Allison Scheidegger Reising
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Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
A courier service as a postal universal service – can a court asses the correctness of a legal qualification of a service of a courier company that was not contested by the company in an earlier decision taken by the postal regulator? Case comment to the judgment of the Supreme Court of 25 April 2007 – Courier services (Ref. No. III SK 2/07) [PDF]
Yearbook of Antitrust and Regulatory Studies, 2008 The President of the Polish Regulatory Office for Telecommunication and Post (hereafter, URTiP) issued in 1994 a decision prohibiting the shipping and transport company A., which was previously granted a concession for the provision of certain shipping ...
Agata Jurkowska
doaj
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
The belief of the hereafter in İslam and the reincarnation
, 2010 Kur'an'da Ölüm Sonrası ve Reenkarnasyon konusunu değişik yonlerden ele almaya, Kur'an'a göre Reenkarnasyon varmıdır, varsa ne şekilde ve nasıldır sorusuna cevap bulmaya çalışılmıştır.The blief of hereafter (Ahiret) is one of the Islam&
Sharivkhan, Galimbek
core
Belief in the hereafter in Alevi-Bektashi sources
, 2019 İnsanlık var olduğundan beri insanlar kendi mahiyetlerini sorgulamışlar ve anlamlandırmaya çalışmışlardır. Yine Tanrı yani Yaratıcı kavramı, insanın neden ve nasıl var olduğu da dünya hayatını anlamlandırması için düşündüğü meseleler olmuştur.
Tarhan, Nebi
core +1 more source
Epigenetic reprogramming of lineage switching in cancer
FEBS Letters, EarlyView.Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source