Results 51 to 60 of about 281,012 (217)

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

FIQIH IBADAH VERSUS FIQIH MUAMALAH

open access: yesEl-Jizya: Jurnal Ekonomi Islam, 2019
People's understanding of fiqh of worship is only a matter for the happiness of the hereafter while understanding muamalah fiqh / Economy is for world happiness only.
Fathul Aminudin Aziz
doaj   +1 more source

Biometric relation between body size and otolith size of Cyprinion kais and C. macrostomum collected from Tigris River, Şirnak Province, Türkiye

open access: yesOceanological and Hydrobiological Studies, 2023
One hundred and twenty asterisci were obtained from 30 specimens each of Cyprinion kais and Cyprinion macrostomum. Significant relationships between otolith mass and the three fish lengths (TL, SL, and FL) were attained for C. kais.
Dörtbudak Muhammed Yaşar   +3 more
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Mortal Combat and the Hereafter: saṃparāya and sāṃparāya in Sanskrit Literature

open access: yesBhasha
Sāṃparāya is a comparatively rare word in Sanskrit literature that has been translated in various ways, among them ‘battle’, ‘the next world’, and ‘transit to the next world’.
Haas, Dominik A.
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Is the parallel competence set out in Regulation 1/2003 totally clear? Case comment to the preliminary ruling of the Court of Justice of 3 May 2011 Tele 2 v Prezes Urzędu Ochrony Konkurencji i Konsumentów (Case C-375/09) [PDF]

open access: yesYearbook of Antitrust and Regulatory Studies, 2012
With a motion dated 28th of April 2005 submitted to the President of the Office of Competition and Consumer Protection (in Polish: Prezes Urzędu Ochrony Konkurencji i Konsumentów; hereafter, UOKiK President), Tele2 Polska Sp. z o.o. (currently: Netia S.A.
Ilona Szwedziak
doaj  

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

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