Results 191 to 200 of about 281,012 (217)

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

Camera-Trap Evidence of <i>Myricaria</i> sp. Consumption and Head-Rubbing by a Wild Snow Leopard (<i>Panthera uncia</i>) in an Alpine Ecosystem. [PDF]

Ecol Evol
Kinoshita K, Yoshimura H, Zhumabai Uulu K, Sharma K, Sergek Uulu A, Djaparov E, Tolok Uulu K, Kikuchi DM.   +7 more
europepmc   +1 more source

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

FEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo, Sandy Richter, Christoph Bach, Wieland Kiess, Anna Kirstein, Diana Le Duc, Antje Garten   +6 more
wiley   +1 more source

Electrocardiographic Manifestation of Modulated Parasystole With Variable Escape Timing. [PDF]

JACC Case Rep
Doss R, Nathan K, Jaiswal J, Kutalek SP, Gupta A.   +4 more
europepmc   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

The Danish Database for Hepatitis B and C (DANHEP): A Nationwide, Prospective, Ongoing Cohort Study. [PDF]

Clin Epidemiol
Bollerup S, Sølund C, Hallager S, Jespersen S, Balslev U, Andersen ES, Pedersen J, Winckelmann A, Barfod TS, Clausen MR, Omland LH, Hobolth L, Madsen LG, Leth S, Mygind LH, Rasmussen TA, Laursen AL, Svensgaard S, Røge B, Tarp B, Thielsen P, Bukh J, Øvrehus A, Christensen PB, Krarup H, Weis N.   +25 more
europepmc   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

FEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss, Ao Li, Eduardo H. Gilglioni, Mayank Bansal, Sumeet Pal Singh, Latifa Bakiri, Alessandra K. Cardozo, Esteban N. Gurzov   +7 more
wiley   +1 more source

Type 2 diabetes does not inevitably shorten life expectancy. [PDF]

Mil Med Res
Du HD.
europepmc   +1 more source

Spatially explicit power analysis reveals challenges for a long-term threatened species monitoring program in Australia. [PDF]

Ecol Appl
Menon V, Southwell D, Robley A, Rees MW, Wilkinson DP, Giljohann K, Pascoe J, Wintle B, Hradsky BA.   +8 more
europepmc   +1 more source

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Women’s Rights in the Hereafter: A Qur’anic Theological Study

2020
exaly