Results 91 to 100 of about 221,327 (302)

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

open access: yesMolecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce   +11 more
wiley   +1 more source

The family novel. Intergenerational novels, family memoirs, changing society in changing fiction forms. New approaches to the family novel in European and American Literature from 1950 to 2010 (FamiLit) - STAR 2014_Linea 1

open access: yes, 2015
The aim of this project is to investigate the characteristics and the main developments of the family novel from 1950 to 2010 in European and American literature.
Francesco Arcidiacono   +6 more
core  

FAKTA SEJARAH DALAM NOVEL PEREMPUAN KEUMALA KARYA ENDANG MOERDOPO

open access: yesCendekia: Jurnal Pendidikan dan Pembelajaran, 2015
This study aims at analyzing historical facts encountered in the novel  Keumala Woman (Perempuan Keumala) written by Endang Moerdopo. The analyses comprises of historical facts about: (1) Keumalahayati, (2) historical events, and (3) places having ...
Wildan Wildan, Mohd. Harun, Yeni Safrida
doaj   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Historical-Literary Essay on Russian Social Novel

open access: yes, 2015
The author of the article introduces not only the history of Russian social novel of the 19th century, but also the theoretical approach to the genre and its varieties. The article presents the history of the generic form and the very term "social novel".

core  

Historical Fiction as a Mixture of History and Romance: Towards the Genre Definition of the Historical Novel

open access: yesPrague Journal of English Studies, 2014
This article focuses on Walter Scott’s Waverley and its classification as the founding text of the historical novel by Georg Lukacs. The author attempts to show that Lukacs takes Scott too much at his word and posits Waverley in the tradition of the ...
Nagy Ladislav
doaj   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

The contemporary British historical novel: representation, nation, empire

open access: yes, 2009
This is the first full-length study of a genre that has had increasing critical attention and popular appeal at the turn of the twenty-first century.
Boccardi, Mariadele
core  

The Stanwick Chronicles: An Historical Novel [PDF]

open access: yes, 2007
I chose as my project to write an historical fiction novel, The Stanwick Chronicles, taking place in seventeenth century England. The reason I chose this particular project was my desire to combine both my English Literature and History majors into one ...
Wanamaker, Kathleen   +1 more
core  

Cormac McCarthy, blood meridian: part 1 [The american novel since 1945]

open access: yes, 2016
Presents a lecture of Professor Hungerford that analyzes McCarthy's Blood Meridian. The book shows the literary tradition and American history and originality.
Hungerford, Amy
core   +1 more source

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