Results 61 to 70 of about 221,327 (302)
The New Historical Novel is a Historical Novel
International Journal of Education, Culture and SocietyIn these lines we expose that nowadays the beginning of a research work no longer has such clear and distinct categories as it was supposed just a few decades ago. The supposed solidity of some concepts is blurring as well as some disciplinary visions that were sure of their rigorous procedure, in fact, only widened the gap between the abstract world ...
openaire +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Abduction : the writing of a historical novel
, 2011 This is a practice-led project consisting of a historical novel Abduction and related exegesis.\ud \ud The novel is a third person intimate narrative set in the mid-nineteenth century and is based on actual events and persons caught up in, or furthering,
MacLeod, Mhairead Ellen
core
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
The contemporary historical novel
, 2011 Although contemporary historical novels share a number of features with the traditional historical novel, as analysed by Lukács (1981) , they display a fundamental change in the perception of history, evident in the disappearance of the omniscient ...
Agnes Heller
core +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
The Great Patriotic War as a Source of Plots for Modern Historical Fantastic Fiction
Филологический класс, 2013 The author focuses on the modern Russian historical fantastic novel as part of modern historical discourse. The characteristics of the typical plot of the genre and the type of the main character are investigated and found interdependent.
doaj
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
The Historical Novel in Australia
, 2003 The essay 'The Historical Novel in Australia' was an intervention into a debate, initiated by novelist Malcolm Knox, that too many historical novels were being published in Australia, to the detriment of an engaged realism.
Falconer, DC
core
, 2021 Tasmanian devils (Sarcophilus harrisii) are evolving in response to a unique transmissible cancer, devil facial tumour disease (DFTD), first described in 1996.
Patton, Austin H +13 more
core +1 more source