Results 111 to 120 of about 3,893,972 (301)

Art and the Human Condition: Incorporating Visual Analysis of Artworks into a Undergraduate Pre-Medicine Curriculum [PDF]

open access: yes, 2012
This thesis project presents a sample class session for the course, The Human Condition: An Arts Perpective (ARTH 361), which will be a part of the optional Medical Humanities minor for the pre-medicine students at Virginia Commonwealth University (VCU)
Fuqua, Elizabeth
core   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

A History of Penicillin: The Miracle of Medicine [PDF]

open access: yes, 2017
Dr. Heather McCreaThe discovery of penicillin in 1928 was a breakthrough in the world of medicine. Bacterial diseases could now be treated rapidly and easily without the long, complex regimens prescribed by doctors before this time. Surprisingly, many in
Rogers, John P.
core  

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

open access: yesMolecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero   +8 more
wiley   +1 more source

History of Medicine Schedule 2010-2011 [PDF]

open access: yes, 2010
William Osler (1849-1919): America’s Most Famous Physician (Robert E. Rakel) The Assassination of John F. Kennedy: A Neurosurgeon’s Eyewitness Account of the Medical Aspect of the Events of November 22, 1963 (Robert G.
Houston History of Medicine Society
core  

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

open access: yesMolecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou   +5 more
wiley   +1 more source

The teaching of the History of Medicine in Italy: a path in progress. [PDF]

open access: yesActa Biomed, 2021
Siri A   +3 more
europepmc   +1 more source

Foot and Mouth Disease: The 1967 outbreak and its aftermath [PDF]

open access: yes, 2003
The transcript of a Witness Seminar held by the Wellcome Trust Centre for the History of Medicine at UCL, London, on 11 December 2001. First published by the Wellcome Trust Centre for the History of Medicine at UCL, 2003.
Reynolds, LA, Tansey, EM
core  

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham   +21 more
wiley   +1 more source

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