Results 121 to 130 of about 343,081 (246)
This study presents a novel AI‐based diagnostic approach—comprehensive serum glycopeptide spectra analysis (CSGSA)—that integrates tumor markers and enriched glycopeptides from serum. Using a neural network model, this method accurately distinguishes liver and pancreatic cancers from healthy individuals.
Motoyuki Kohjima +6 more
wiley +1 more source
Critical medical humanities: embracing entanglement, taking risks [PDF]
William Viney +2 more
openalex +1 more source
Discipline and Punish in the Humanities: A Philosophically Indisciplined Manifesto
Doru Pop
openalex +1 more source
Information technology and the humanities scholar: Documenting digital research practices
L. Given, Rebekah Willson
semanticscholar +1 more source
β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero +8 more
wiley +1 more source
Regionale Wirtschaftsgeschichte, Historische Demographie und Digital Humanities
Katrin Moeller
openalex +1 more source
Modelling in digital humanities: Signs in context [PDF]
Arianna Ciula, Øyvind Eide
openalex +1 more source
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou +5 more
wiley +1 more source
NEW APPROACHES TO ANCIENT SPATIAL MODELS: DIGITAL HUMANITIES AND CLASSICAL GEOGRAPHY [PDF]
Chiara Palladino
openalex +1 more source
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham +21 more
wiley +1 more source

