Results 131 to 140 of about 1,516,008 (339)

Integration of circadian and hypoxia signaling via non‐canonical heterodimerization

FEBS Letters, EarlyView.
CLOCK, BMAL1, and HIFs are basic helix‐loop‐helix and Per‐Arnt‐Sim domain (bHLH‐PAS) proteins, which function as transcription factors. bHLH‐PAS proteins are designated in two classes. Many class I proteins are regulated by environmental signals via their PAS domains, but such signals have not been identified for all.
Sicong Wang, Katja A. Lamia
wiley   +1 more source

Arts and Humanities Education: A Systematic Review of Emerging Technologies and Their Contribution to Social Well-Being

The social science
The purpose of this study is to identify the most applied emerging technologies in the field of arts and humanities, exploring their advantages and potential obstacles. The research results aim to contribute to social and cultural well-being by enhancing
Nancy Usca, Mariela Samaniego, Carlos Yerbabuena, Isaac Pérez   +3 more
semanticscholar   +1 more source

Life on a Nickels Edge Struggle and Dignity in Buffalo\u27s Fruit Belt [PDF]

, 2017
This purpose of this fact sheet is to give a brief overview of the Fruit Belt neighborhood on Buffalo’s East Side in relation to community demographics, development, and efforts to control land use through the creation of the FB Community Land Trust ...
Marsland, John
core   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source

ELAN as flexible annotation framework for sound and image processing detectors [PDF]

, 2010
Annotation of digital recordings in humanities research still is, to a largeextend, a process that is performed manually. This paper describes the firstpattern recognition based software components developed in the AVATecH projectand their integration in
Auer, E., Masnieri, S., Russel, A., Schneider, D., Schreer, O., Sloetjes, H., Tschöpel, S., Wittenburg, P.   +7 more
core   +1 more source

Towards an innovative model of complementary opposites analysis in the field of sciences and humanities [PDF]

, 2019
Humberto Ortega Villaseñor
openalex   +1 more source

Mechanisms of parasite‐mediated disruption of brain vessels

FEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira, Sílvia Arroz‐Madeira, Cláudio A. Franco, Sara Silva Pereira   +3 more
wiley   +1 more source

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

FEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf, Nicholas F. Downing, Kaitlyn M. Mills, Samuel C. Metcalfe, Alexander E. Kritzer, Lindsey D. Mayo, Peter C. Hollenhorst   +6 more
wiley   +1 more source