Results 151 to 160 of about 1,516,008 (339)
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Open Access – What’s New in the Arts & Humanities?
Learn about some of the newest open access publications and platforms designed to support the open sharing of humanities research. Join a discussion with librarian liaisons to arts and humanities departments about how Gettysburg faculty and the library ...
Scholarly Communications,
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Is UK humanities research reaching the widest possible audience? [PDF]
Report points to 'serious dangers for the international standing of UK research' in humanities and social sciences. Today marks the launch of another report on open access, a topic area that is rapidly becoming saturated.
Eve, Martin Paul
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A qualitative approach to scientific publications in the Humanities: the researchers' point of view
Evelyn-Paola Guillén-Chávez +7 more
openalex +2 more sources
PICALM::MLLT10 translocated leukemia
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen +7 more
wiley +1 more source
Statistical Analysis of Humanities and Social Sciences Collaboration Research in China [PDF]
With the development of humanities and social sciences, research collaboration becomes more and more important. This article studies collaboration phenomena of seventeen kinds of journals’ from 1995-2004 in china.
Chunlin, Jiang, Yongxia, Liang
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Cell wall target fragment discovery using a low‐cost, minimal fragment library
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
At low cell density, SETDB1 and YAP1 accumulate in the nucleus. As cell density increases, the Hippo pathway is gradually activated, and SETDB1 is associated with increased YAP1 phosphorylation. At high cell density, phosphorylated YAP1 is sequestered in the cytoplasm, while SETDB1 becomes polyubiquitinated and degraded by the ubiquitin–proteasome ...
Jaemin Eom +3 more
wiley +1 more source

