Results 211 to 220 of about 229,937 (298)

Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib

Molecular Oncology, EarlyView.
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute, Júlia Huguet‐Pradell, Jordi Abril‐Fornaguera, Albert Gris‐Oliver, Alex Rialdi, Elisa Fernández‐Martínez, Carla Montironi, Vanessa Del Pozo, Peter Houghton, Laura Zanatto, Agavni Mesropian, Ieva Keraite, Swan Thung, Carolina Armengol, Pau Sancho‐Bru, Ernesto Guccione, Roser Pinyol, Josep M. Llovet   +17 more
wiley   +1 more source

Correction: Iqbal et al. Breast Cancer Inhibition by Biosynthesized Titanium Dioxide Nanoparticles Is Comparable to Free Doxorubicin but Appeared Safer in BALB/c Mice. <i>Materials</i> 2021, <i>14</i>, 3155. [PDF]

Materials (Basel)
Iqbal H, Razzaq A, Uzair B, Ain NU, Sajjad S, Althobaiti NA, Albalawi AE, Menaa B, Haroon M, Khan M, Khan NU, Menaa F.   +11 more
europepmc   +1 more source

SELF-LEARNING OF FOREIGN LANGUAGE STUDENTS IN THE CREDIT SYSTEM HELD AT THE UNIVERSITY OF SOCIAL SCIENCES AND HUMANITIES: PROBLEMS AND SOLUTIONS

, 2011
Thanh Minh To
openalex   +2 more sources

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

Molecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller, Susanne Ebner, Carmen Haselrieder, Julia K. Günther, Astrid Drasche, Sophie Strich, Chiara Volani, Andrea Medici, Aleksandar Nikolajevic, Alex Deltedesco, Johannes E. Sigmund, Michael J. Blumer, Martin Hermann, Johanna Vanacker, Gerald Brandacher, Eduard Stefan, Omar Torres‐Quesada, Jakob Troppmair   +17 more
wiley   +1 more source

Correction: Trend change in delayed first antenatal care visit among reproductive‑aged women in ethiopia: multivariate decomposition analysis. [PDF]

Reprod Health
Gebeyehu AA, Muche AA, Woldemariam M, Yenew C, Atikilt G, Andualem M, Mebrat A.   +6 more
europepmc   +1 more source

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

Molecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola, Rafael Lopes Goncalves, Marin Truchi, Caroline Lacoux, Célia Scribe, Hugo Cadis, Laetitia Guardini, Sophie Bekisz, Marius Ilié, Paul Hofman, Georges Vassaux, Bernard Mari, Roger Rezzonico   +12 more
wiley   +1 more source

The space humanities

Revista Chilena de Literatura, 2012
Bernardo Subercaseaux
doaj  

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

Molecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone, James Dunford, Eleanor Calcutt, Vicki Gamble, Filiz Senbabaoglu Aksu, Lorena Ligammari, Georgina Wherry, Giorgia Gaeta, John C. Christianson, Adrienne M. Flanagan, Udo Oppermann, Adam P. Cribbs   +11 more
wiley   +1 more source

In love with medical humanities! A survey on medical students' opinions and satisfaction with an integrated elective course. [PDF]

BMC Med Educ
Tusoni F, Ferrara V, Franceschini A, Cofini V, Giusti L, Iagnemma A, Romano S, Necozione S, Fabiani L.   +8 more
europepmc   +1 more source

Review of <em>New Arenas for Community Social Work Practice with Urban Youth: Use of the Arts, Humanities, and Sports.</em> Melvin Douglas. Reviewed by Julian Chow

, 2001
Julian Chun‐Chung Chow
openalex   +2 more sources