Results 281 to 290 of about 1,428,010 (391)

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

Molecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero, Alejandro Belmonte‐Fernández, Mónica González‐Moreno, Laura Rodríguez‐Cordero, Begoña Pérez‐Valderrama, Joaquín Herrero‐Ruíz, Francisco Romero, Carmen Sáez, Miguel Á. Japón   +8 more
wiley   +1 more source

Comments on 'Global research trends in tongue cancer from 2000 to 2022: bibliometric and visualized analysis', by Wu et al. [PDF]

Clin Oral Investig
Ho YS, Christidis N.
europepmc   +1 more source

Formal Study in the Humanities? Get Real [PDF]

, 2011
Gambescia, Stephen F.
core   +1 more source

The critical role of DNA damage‐inducible transcript 4 (DDIT4) in stemness character of leukemia cells and leukemia initiation

Molecular Oncology, EarlyView.
Stemness properties, including quiescence, self‐renewal, and chemoresistance, are closely associated with leukemia relapse. Here, we demonstrate that DNA damage‐inducible transcript 4 (DDIT4) is induced in the hypoxic bone marrow niche and is essential for maintaining the stemness of AML1‐ETO9a leukemia cells.
Yishuang Li, Zhijie Cao, Haiyan Xing, Zhenya Xue, Wenbing Liu, Jiayuan Chen, Yihan Mei, Runxia Gu, Hui Wei, Shaowei Qiu, Min Wang, Qing Rao, Jianxiang Wang   +12 more
wiley   +1 more source

Correction: The impact of digital health technologies on moral responsibility: a scoping review. [PDF]

Med Health Care Philos
Meier E, Rigter T, Schijven MP, van den Hoven M, Bak MAR.   +4 more
europepmc   +1 more source

Book Reviews : Scholars and Personal Computers: Microcomputing in the Humanities and Social Sciences

, 1989

openalex   +1 more source

Unveiling unique protein and phosphorylation signatures in lung adenocarcinomas with and without ALK, EGFR, and KRAS genetic alterations

Molecular Oncology, EarlyView.
Proteomic and phosphoproteomic analyses were performed on lung adenocarcinoma (LUAD) tumors with EGFR, KRAS, or EML4–ALK alterations and wild‐type cases. Distinct protein expression and phosphorylation patterns were identified, especially in EGFR‐mutated tumors. Key altered pathways included vesicle transport and RNA splicing.
Fanni Bugyi, Mirjam Balbisi, Simon Sugár, Lóránd Váncza, Eszter Regős, Ilona Kovalszky, Ibolya Laczó, Tünde Harkó, Gábor Kecskeméti, Zoltán Szabó, Judit Moldvay, László Drahos, Lilla Turiák   +12 more
wiley   +1 more source

The association between widowhood duration and depressive symptoms among Chinese older adults: mediation role of sleeping duration and dietary diversity. [PDF]

Eur J Ageing
Mu Y, Wang R, Li Z, Liu Q, Peng J.
europepmc   +1 more source

Marxism and the Philosophy of Science. Atlantic Highlands, New Jersey: Humanities Press, 1985. H. Sheenan

, 1986
S.N. Balagangadhara
openalex   +2 more sources

DASCH: Data and Service Center for the Humanities

Digital Scholarship in the Humanities, 2015
L. Rosenthaler, P. Fornaro, C. Clivaz
semanticscholar   +1 more source