Results 301 to 310 of about 1,428,010 (391)

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

Molecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou, Zhen Wang, Fei Yang, Xiao Han, Lei Li, Huadong Liu   +5 more
wiley   +1 more source

Author Correction: A comprehensive overview of the burden, prevention, and therapeutic aspects of arboviral diseases in India. [PDF]

Commun Med (Lond)
Gupta H, Barde PV, Singh MP, Bharti PK, Nitika N.   +4 more
europepmc   +1 more source

The Effect of Teaching Medical Ethics on Medical Studentsʼ Moral Reasoning. Self DJ, Wolinsky FD, Baldwin DC (Depts of Humanities in Medicine, Philosophy, and Pediatrics, Texas A&M Univ, College Station, TX; Depts of Sociology and Humanities in Medicine, Texas A&M Univ; American Medical Association, Chicago, IL), Academic Medicine 64:755-759, 1989.

, 1990
Ann L Clawson
openalex   +1 more source

Single‐cell transcriptomics redefines focal neuroendocrine differentiation as a distinct prostate cancer pathology

Molecular Oncology, EarlyView.
Single‐cell transcriptomics of prostate cancer patient‐derived xenografts reveals distinct features of neuroendocrine (NE) subtypes. Tumours with focal NE differentiation (NED) share transcriptional programmes with adenocarcinoma, differing from large and small cell neuroendocrine prostate cancer (NEPC). Our work defines the molecular landscape of NEPC,
Rosalia Quezada Urban, Shivakumar Keerthikumar, Ashlee Clark, Hong Wang, Belinda Phipson, Andrew Bakshi, Andrew Ryan, Heather Thorne, Renea A. Taylor, Mitchell G. Lawrence, Gail P. Risbridger, Roxanne Toivanen, David L. Goode   +12 more
wiley   +1 more source

Corrigendum: Deep brain stimulation and suicide attempts in treatment-resistant patients: a case report and neuroethical analysis. [PDF]

Front Psychiatry
D'Imperio A, Ienca M.
europepmc   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

Molecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan, Irina Primac, Emre Etlioglu, Laurens Debruyne, Ann Janssen, Magy Sallam, Kevin Tabury, Roel Quintens, Wiebren Tjalma, Mohammed Abderrafi Benotmane   +9 more
wiley   +1 more source

Practical wisdom and the integration of science and humanism in medicine. [PDF]

Med Educ
Kaldjian LC.
europepmc   +1 more source

Microglia limit brain tumor development by restricting tumor cell proliferation and inducing T‐cell immunity

Molecular Oncology, EarlyView.
Microglia (BV2) and IL‐4‐treated BMDMs promote astrocytoma clustering and inhibit tumor growth, not shown in other macrophage cells. In vivo, microglial co‐implantation enhances CD8+ T cell infiltration, elevates Granzyme B, lowers circulating MDSCs, and extends survival only in immune‐competent mice, but not in immune‐deficient mice.
Tzu‐Chieh Sun, Ching‐Fang Yu, Sheng‐Yan Wu, Wei‐Chung Cheng, Chi‐Shiun Chiang, Fang‐Hsin Chen   +5 more
wiley   +1 more source

Didier Alexandre et Glenn Roe (éd.), Observer la vie littéraire. Études littéraires et numériques

Humanités Numériques
Riccardo Barontini
doaj   +1 more source

Hearing Patient Stories: Use of Medical Humanities on a Large-Scale, Virtual Platform to Improve Clinician Engagement. [PDF]

Fed Pract
Rossiter B, Farkas A, Kolehmainen C, McNeil M, Merriam S.   +4 more
europepmc   +1 more source