Results 61 to 70 of about 343,081 (246)
FEBS Letters, EarlyView.Atovaquone is an antimalarial requiring potentiation for sufficient efficacy. We pursued strategies to enhance its activity, showing that 4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase, decreasing ubiquinone biosynthesis. Since atovaquone competes with ubiquinol in mitochondria, 4‐nitrobenzoate facilitates its action, potentiating ...
Ignasi Bofill Verdaguer +7 more
wiley +1 more source
Computation and the Humanities
Springer Series on Cultural Computing, 2016 This book looks at the application of computing to cultural heritage and how it is transforming how the human record can be transmitted and understood.
J. Nyhan, Andrew Flinn
semanticscholar +1 more source
FEBS Letters, EarlyView.Cells must clear mislocalized or faulty proteins from membranes to survive. The AAA+ ATPase Msp1 performs this task, but dissecting how its six subunits work together is challenging. We engineered linked dimers with varied numbers of functional subunits to reveal how Msp1 subunits cooperate and use energy to extract proteins from the lipid bilayer ...
Deepika Gaur +5 more
wiley +1 more source
The Rise and Fall Tool-Related Topics in CHum
Digital Studies, 2016 What can we learn from the discourse around text tools? More than might be expected. The development of text analysis tools has been a feature of computing in the humanities since IBM supported Father Busa's production of the Index Thomisticus (Tasman ...
Amy Dyrbye +3 more
doaj +1 more source
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Актуальні питання суспільних наук та історії медицини, 2014 Troyanskyy Volodymyr. Methodological Problems of Social and Humanitarian Knowledge The ambiguity of spiritual diagnoses of "spiritual illness" of Ukrainian society necessitates the deeper research in field of the humanities, methodological problems of ...
Троянський Володимир
doaj
The Encounter of Nursing and the Clinical Humanities: Nursing Education and the Spirit of Healing
Humanities, 2014 Practicing the clinical humanities requires throwing oneself into the unpredictable locus of suffering, where one is unable to infer the actual situation of the other, a process which fosters self-disclosure.
An-bang Yu
doaj +1 more source
Four Claims on Research Assessment and Metric Use in the Humanities
Bulletin of the Association for Information Science and Technology, 2017 EDITOR'S SUMMARYBibliometric evaluation for research in the field of sciences can be a good way to assess the quality and factual basis of claims and can lead to more funding for authors and for research work.
Björn Hammarfelt
semanticscholar +1 more source
Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
Open Access Publishing Models and How OA Can Work in the Humanities
Bulletin of the Association for Information Science and Technology, 2017 EDITOR'S SUMMARYOpen access (OA) has been shaping and benefitting the scientific community for years now, but this new wave of disseminating research freely has not quite taken hold in the field of humanities.
M. Eve
semanticscholar +1 more source