Results 131 to 140 of about 82,262 (248)

Text semantics as a prime cause of the subject and the characters' behaviour (or: Why the duke Lev Nikolayevich stayed with Nastsya Philippovna, but not with Aglaya)

open access: yesRUDN Journal of Language Studies, Semiotics and Semantics, 2010
The article represents an example and realization of the philological hermeneutical commentary of parts of F.M. Dostoyevsky novel «The Idiot».
О I Valentinova
doaj  

Efficacy of a Multicomponent Intervention for Frailty or Physical Function in Prefrail or Frail Older Adults: FRAILMERIT Multicenter Clinical Trial

open access: yesJournal of the American Geriatrics Society, Volume 74, Issue 3, Page 658-668, March 2026.
Clinical management of the older adult. ABSTRACT Objectives Frailty is a common condition in community‐dwelling older adults with high health and socioeconomic implications. However, primary care‐led randomized trials have been scarcely tested. Design Multicenter cluster randomized clinical trial.
Adriana Abizanda Saro   +86 more
wiley   +1 more source

Prefrontal Cortex Dysfunction as a Precipitating Factor for Schizophrenia and Depression

open access: yesJournal of Neurochemistry, Volume 170, Issue 3, March 2026.
Stress during adolescence or adulthood affects the ability of the prefrontal cortex (PFC) to adaptively regulate stress. Maladaptive adult stress leads to PFC hypofunction and a hypodopaminergic state in the medial, affect‐related ventral tegmental area (VTA), resulting in amotivation.
Daniela L. Uliana, Anthony A. Grace
wiley   +1 more source

Facing hard truths: Medical education's reckoning with settler colonialism in an era of reconciliation

open access: yesMedical Education, Volume 60, Issue 3, Page 317-325, March 2026.
Abstract Introduction Medical schools are responsible for embedding Indigenous health education across the training continuum. Central to this work is recognising settler colonialism as an ongoing structure that privileges non‐Indigenous peoples while producing and sustaining inequities for Indigenous communities.
Obinna Esomchukwu   +4 more
wiley   +1 more source

Characterization of Phytoene Desaturase Knockout Carotenoid‐Deficient Microalgal Mutants Generated by Cas9‐Ribonucleoprotein Complexes

open access: yesPhysiologia Plantarum, Volume 178, Issue 2, March/April 2026.
ABSTRACT Phytoene desaturase (PDS; EC 1.3.5.5) is a key enzyme of the carotenoid biosynthetic pathway, catalyzing the desaturation of phytoene, precursor of all carotenoids. In this study, several PDS‐knockout (PDS‐KO) transformants of the chlorophyte microalga Chlamydomonas reinhardtii were generated using a reverse genetics strategy. Two single guide
Ana Molina‐Márquez   +5 more
wiley   +1 more source

Once Again on the Original Pictorial Plot in F. M. Dostoyevsky’s The Idiot

open access: yesИзвестия Уральского федерального университета. Серия 2: Гуманитарные науки, 2015
The system of characters in F. M. Dostoyevsky’s The Idiot is considered in the article. The system is created according to the principle of opposition and is part of the novel’s visual range.
Natalya Sergeyevna Rubtsova
doaj  

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