Results 71 to 80 of about 4,925,508 (271)

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

open access: yesMolecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg   +43 more
wiley   +1 more source

Maximal Cost-Bounded Reachability Probability on Continuous-Time Markov Decision Processes

open access: yes, 2014
In this paper, we consider multi-dimensional maximal cost-bounded reachability probability over continuous-time Markov decision processes (CTMDPs). Our major contributions are as follows.
Fu, Hongfei
core   +1 more source

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

open access: yesMolecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix   +13 more
wiley   +1 more source

A comparative analysis of intravenous infusion methods for low-resource environments

open access: yesFrontiers in Medicine
IntroductionIntravenous (IV) therapy is a crucial aspect of care for the critically ill patient. Barriers to IV infusion pumps in low-resource settings include high costs, lack of access to electricity, and insufficient technical support.
Oluwakemi Tomobi   +12 more
doaj   +1 more source

A brief description of the Medical Information Computer System (MEDICS) [PDF]

open access: yes
The Medical Information Computer System (MEDICS) is a time shared, disk oriented minicomputer system capable of meeting storage and retrieval needs for the space- or non-space-related applications of at least 16 simultaneous users.
Moseley, E. C.
core   +1 more source

Structural modelling of cost overrun factors in construction industry [PDF]

open access: yes, 2013
Construction industry contributes significantly in improving socio-economic growth of a country. However, this industry usually faces chronic problems such as time overrun, cost overrun, poor quality and others.
Memon, Aftab Hameed
core  

Minimizing the Cost of Team Exploration

open access: yes, 2019
A group of mobile agents is given a task to explore an edge-weighted graph $G$, i.e., every vertex of $G$ has to be visited by at least one agent. There is no centralized unit to coordinate their actions, but they can freely communicate with each other ...
BL Golden   +13 more
core   +1 more source

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

open access: yesMolecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris   +10 more
wiley   +1 more source

The Odyssey Approach for Optimizing Federated SPARQL Queries

open access: yes, 2017
Answering queries over a federation of SPARQL endpoints requires combining data from more than one data source. Optimizing queries in such scenarios is particularly challenging not only because of (i) the large variety of possible query execution plans ...
A Schwarte   +7 more
core   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon   +9 more
wiley   +1 more source

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