Results 161 to 170 of about 5,136 (295)

Effect of terahertz irradiation on DNA damage repair in living cells

FEBS Open Bio, EarlyView.
We investigated the effect of terahertz (THz) wave irradiation on DNA double‐strand break (DSB) repair in living cells. We found that THz irradiation enhanced DSB repair at specific frequencies, whereas heat treatment inhibited it, indicating that this effect is nonthermal and frequency‐specific.
Yuya Ueno, Shota Yamazaki, Hiromichi Hoshina, Masahiko Harata   +3 more
wiley   +1 more source

"I feel like so much more of myself": The experience of modifying appearance in borderline personality disorder. [PDF]

Personal Disord
Jones KG, Allan T, Furtado Fernandes L, Zhang S, Conaway N, Umeugo A, Masland SR, Nelson S, Fineberg SK.   +8 more
europepmc   +1 more source

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

FEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana, Avigail Yariv, Tal Oppenheim, Hadar Amartely, Dana Reichmann, Oded Livnah   +5 more
wiley   +1 more source

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

Aging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang, Zhong Fan, Runmeng Liu, Xiaotian Zhang   +3 more
wiley   +1 more source

Three types of actomyosin rings within a common cytoplasm exhibit distinct modes of contractility. [PDF]

Mol Biol Cell
Linehan JB, Zampetaki A, Werner ME, Heck B, Maddox PS, Fürthauer S, Maddox AS.   +6 more
europepmc   +1 more source

Risk Prediction Models for Recurrence After Curative Treatment of Early‐Stage or Locally Advanced Lung Cancer: A Systematic Review

Aging and Cancer, EarlyView.
This systematic review synthesizes prognostic models for survival and recurrence in resected non‐small cell lung cancer. While many models demonstrate moderate to good discrimination, few are externally validated and reporting quality is variable, limiting clinical applicability and highlighting the need for robust, transparent model development ...
Evangeline Samuel, S. Tissera, E. Paul, J. Zalcberg, R. G. Stirling   +4 more
wiley   +1 more source

Discretion and contextual influences on creative thinking. [PDF]

Front Psychol
Tadik H, Runco MA, Bahar K.
europepmc   +1 more source

Mechanistic Analysis of Stereodivergent Nitroalkane Cyclopropanation Catalyzed by Nonheme Iron Enzymes. [PDF]

J Am Chem Soc, 2023
Ushimaru R, Cha L, Shimo S, Li X, Paris JC, Mori T, Miyamoto K, Coffer L, Uchiyama M, Guo Y, Chang WC, Abe I.   +11 more
europepmc   +1 more source

Profound Leadership Strategies: Transcending the Leadership Crisis in the Age of Artificial Intelligence

New Directions for Adult and Continuing Education, EarlyView.
ABSTRACT This article examines the evolving role of organizational leadership amidst the rapid advancements in artificial intelligence (AI). It explores a broadly experienced and documented crisis in leadership, due in part to the disruptive nature of AI and emerging technology.
Rachel Wlodarsky, Davin Carr Chellman
wiley   +1 more source

Rings of Power: Symbolism of Power and Corruption in Tolkien’s The Lord of the Rings and The Silmarillion [PDF]

This thesis analyzes the power and influence of the One Ring in J. R. R. Tolkien’s The Lord of the Rings and The Silmarillion. It looks at some other prominent examples of magic rings throughout history and mythology which have influenced and inspired ...
Jakopić, Benjamin
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