Results 61 to 70 of about 127,278,237 (294)

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Denial of Service Attack Techniques: Analysis, Implementation and Comparison [PDF]

Journal of Systemics, Cybernetics and Informatics, 2005
A denial of service attack (DOS) is any type of attack on a networking structure to disable a server from servicing its clients. Attacks range from sending millions of requests to a server in an attempt to slow it down, flooding a server with large ...
Khaled Elleithy, Drazen Blagovic, Wang Cheng, Paul Sideleau   +3 more
doaj  

Elite coaches’ opinion about the additional court player and the strategic-tactical structures in handball

Motriz: Revista de Educacao Fisica, 2019
Aim: To investigate the speeches of elite handball coaches about the current strategic-tactical configuration after the rule change that allows the use of the seventh court player in the attack.
Tathyane Krahenbühl, Rafael Pombo Menezes, Lucas Leonardo   +2 more
doaj   +1 more source

Cyber-Attacks Risk Analysis Method for Different Levels of Automation of Mining Processes in Mines Based on Fuzzy Theory Use

Sensors, 2020
The rising automation level and development of the Industry 4.0 concept in the mining sector increase the risk of cyber-attacks. As a result, this article focuses on developing a risk analysis method that integrates Kaplan’s and Garrick’s approach and ...
Agnieszka A. Tubis, Sylwia Werbińska-Wojciechowska, Mateusz Góralczyk, Adam Wróblewski, Bartłomiej Ziętek   +4 more
doaj   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

Insider attacks as one of the main threats to resolute support personnel in Afghanistan

Security and Defence Quarterly, 2016
<i>From July 2015, the International Security Assistance Force (ISAF) moved into the Resolute Support Mission (RSM) and started acting in the supporting role. From that time, one of the most important Security Force Assistance tasks has been maintaining and developing relationships with its counterparts in the Afghan Security Institutions (ASI ...
openaire   +2 more sources

Effect of Planting Dates on the Main Pests Attacking Squash Plants in Mansoura Region [PDF]

Journal of Plant Protection and Pathology, 2018
The present experiments were conducted at the experimental farm belonging to the faculty of agriculture, Mansoura University. The squash plants (var. Eskandrani) was cultivated in the beginning of the third week of March, the first week of June, and the second week of August during the two successive seasons (2014 and 2015).
S. Awadalla, Hala El-Serafi, M. El-Naggar, Marwa El-Mesawy   +3 more
openaire   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

Authorisation, attack detection and avoidance framework for IoT devices

IET Networks, 2020
Internet of Things (IoT) involve large volumes of data generated from the interactions between devices and people, and security is a main alarm in IoT.
Pradeep Sudhakaran, Chidambaranathan Malathy   +1 more
doaj   +1 more source