Results 121 to 130 of about 9,555,785 (358)

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

Business and News Media Perspectives on the Power of Social Media Publics : Case Finland

open access: yes, 2018
The Internet, social media, and their varied online publics have affected the working processes of public relations (PR) practitioners and journalists.
Sormanen, Niina
core  

Political Relational Influencers: The Mobilization of Social Media Influencers in the Political Arena

open access: yesInternational Journal of Communication, 2023
Social media platforms are a powerful tool to exert influence and impress opinions—for commercial operators, brands, and political campaigns. Influencers can help campaigns reach specific audiences and convey support for issues and candidates.
Anastasia Goodwin   +4 more
doaj  

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

THE IMPACT OF MEDIA ON THE ECONOMIC AND POLITICAL DEVELOPMENT OF THE EU DURING THE 2008 CRISIS

open access: yesВестник Кемеровского государственного университета, 2013
The paper researches the impact of media on specific economic and political processes that have been going on in the EU during the crisis of 2008 and up to the present time.
V. G. Dorohov
doaj  

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

Media Cloud: Massive Open Source Collection of Global News on the Open Web

open access: yes
2021 Fifteenth International AAAI Conference on Web and Social MediaWe present the first full description of Media Cloud, an open source platform based on crawling hyperlink structure in operation for over 10 years, that for many uses will be the best ...
Valiukas, Linas   +17 more
core   +1 more source

The triple articulation of media technologies in audiovisual media consumption

open access: yes, 2013
This article departs from the concept of “double articulation” within domestication theory, which views media as both objects and texts. Unfortunately, its empirical application has been problematic because researchers tend to concentrate on the ...
De Marez, L.   +11 more
core   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Domination and the arts of digital resistance in social media Creator labor [PDF]

open access: yes
This article conducts a collaborative qualitative thematic analysis of in-depth interviews with social media content creators (N = 53) based in and/or originated from the United Kingdom.
Saunders, Rebecca, Salamon, Errol
core   +1 more source

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