Results 261 to 270 of about 9,555,785 (358)

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

Evaluating the involvement of autolysosomes in the nuclear translocation of fluorescent proteins

FEBS Open Bio, EarlyView.
Endogenously expressed fluorescent proteins can be degraded by autophagy and transported to cell nuclei via the nuclear pore complex. But in some cell lines, for example, HeLa cells which are positive for immunoreactivity of a receptor ligand, such as UCN I, in cell nuclei, fusion of autolysosome with the nuclear envelope is involved in the nuclear ...
Keiichi Ikeda
wiley   +1 more source

Disparities in Evidence and Media Portrayal of Injectable Orthobiologics for Knee Osteoarthritis: A Systematic Review of Randomized Trials and News Media. [PDF]

Orthop J Sports Med
Zhang EJX, Tay RWL, Hui JHP, Tan BWL.
europepmc   +1 more source

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

FEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim, Marco Corazzari, Iman Osman, Jane Armstrong, Noel Carter   +4 more
wiley   +1 more source

The Influence of Social Media Messaging on Human Papillomavirus Vaccine Attitudes and Confidence Among Adolescent Males: Group Discussion Study. [PDF]

JMIR Cancer
Trivedi N, Van Vleet R, Eid C, Burke-Garcia A, Leader AE.   +4 more
europepmc   +1 more source

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

FEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo, Sandy Richter, Christoph Bach, Wieland Kiess, Anna Kirstein, Diana Le Duc, Antje Garten   +6 more
wiley   +1 more source

Fear of missing out (FoMO) in the digital age: implications for academic productivity and sleep quality among Saudi university students. [PDF]

Front Psychol
Alzahrani F, Raidan R, Al Harbi W, Aljutily SS, Almuzainy L, Aljohani J, Aljohani E, Alrefaei M, Aljohani S, Alorfi Y, Al Thaqfan SS, Fallatah SB, Alolayan SO, Habeeb E, Alnezary FS.   +14 more
europepmc   +1 more source

Prostate cancer research on social media platforms: a bibliometric and thematic analysis. [PDF]

Front Oncol
Xie Y, Huang H, Chen X, Chen L, Guo Z.
europepmc   +1 more source

Exposure to e-cigarette content on social media and its association with risk perception, perceived benefits, and vaping perceptions among college students: a cross-sectional study. [PDF]

Front Public Health
Alsulaiman SA, Almutairi ES.
europepmc   +1 more source