Results 111 to 120 of about 1,768,787 (301)
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Back to the Middle Ages: Entomological and Botanical Elements Reveal New Aspects of the Burial of Saint Davino of Armenia. [PDF]
Loni A +5 more
europepmc +1 more source
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
At the beginning of the 11th Century, in the variegated universe that characterized the monastic religious orders with hermit tendencies, or monastic brotherhoods, and religious organizations, the choice of the habit began to take on profound ...
Diana Del Mastro
doaj
The Medical Historical Cultural Foundations of Western Nasal Surgery from Ancient Greece to the Middle Ages. [PDF]
Marinozzi S +6 more
europepmc +1 more source
The role of histone modifications in transcription regulation upon DNA damage
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley +1 more source
BERDE (BERZA’A) A CITY OF CIVILISATION IN THE MIDDLE AGES
The city has been the most important symbol of merciless struggle against nature in mankind history since people started to live together. Cities, as places, have been one of the most important indicators of civilizations where humans have fulfilled ...
Mehmet Özmenli
doaj
Walruses on the Dnieper: new evidence for the intercontinental trade of Greenlandic ivory in the Middle Ages. [PDF]
Barrett JH +7 more
europepmc +1 more source
Some Remarks on Averroes’ Long Commentary on the Metaphysics Book Alpha Meizon [PDF]
Averroes, considered to be the greatest Aristotelian commentator in the Middle Ages, has written three different types of commentary on almost all the works of this great philosopher: short, middle and long.
Altuner, Ilyas
core +1 more source
Function‐driven design of a surrogate interleukin‐2 receptor ligand
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source

