Results 111 to 120 of about 1,768,787 (301)

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

open access: yesFEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Il nero di Cluny contro il bianco di Cîteaux: aspetti simbolici e cromatici degli abiti monastici medievali

open access: yesColloquia Theologica Ottoniana, 2013
At the beginning of the 11th Century, in the variegated universe that characterized the monastic religious orders with hermit tendencies, or monastic brotherhoods, and religious organizations, the choice of the habit began to take on profound ...
Diana Del Mastro
doaj  

The Medical Historical Cultural Foundations of Western Nasal Surgery from Ancient Greece to the Middle Ages. [PDF]

open access: yesAesthetic Plast Surg, 2023
Marinozzi S   +6 more
europepmc   +1 more source

The role of histone modifications in transcription regulation upon DNA damage

open access: yesFEBS Letters, EarlyView.
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley   +1 more source

BERDE (BERZA’A) A CITY OF CIVILISATION IN THE MIDDLE AGES

open access: yesZeitschrift für die Welt der Türken, 2014
The city has been the most important symbol of merciless struggle against nature in mankind history since people started to live together. Cities, as places, have been one of the most important indicators of civilizations where humans have fulfilled ...
Mehmet Özmenli
doaj  

Walruses on the Dnieper: new evidence for the intercontinental trade of Greenlandic ivory in the Middle Ages. [PDF]

open access: yesProc Biol Sci, 2022
Barrett JH   +7 more
europepmc   +1 more source

Some Remarks on Averroes’ Long Commentary on the Metaphysics Book Alpha Meizon [PDF]

open access: yes, 2017
Averroes, considered to be the greatest Aristotelian commentator in the Middle Ages, has written three different types of commentary on almost all the works of this great philosopher: short, middle and long.
Altuner, Ilyas
core   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

open access: yesFEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang   +9 more
wiley   +1 more source

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