Results 71 to 80 of about 127,283,970 (300)
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Forming peculiarities of ethnocultural policy of China in the early Middle Ages
RUDN Journal of World History, 2013 The problem of ethnic and cultural contacts with the non-Chinese people in China in the early medieval period shows an important feature of Chinese civilization, which consists in the fact that all the elements brought about gradually adapting and become
E Borisovna Barinova
doaj
The borders of the adverbium between praepositio and coniunctio in Notker’s perspective
The Journal of Classics TeachingThe discovery of Priscian’s Institutiones Grammaticae brought a new perspective to the grammatical analysis of the eighth and ninth centuries, as it heavily relied on the commentaries on Donatus’s Ars Minor and Ars Maior, and many scholars of the time ...
Paola Cotticelli-Kurras +1 more
doaj +1 more source
FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Ancient Russian Materials in the Perm Cis-Urals During the 10th–11th Centuries
Поволжская археология, 2017 The article examines the interaction of the Middle Cis-Urals with Russia as an important factor in ethnic and cultural process in the Middle Ages. During the 10th –11th centuries, this interaction was based on trade relations alongside with active ...
Belavin Andrey M., Krylasova Natalia B.
doaj +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Управленческое консультирование, 2018 The article discusses the role of war in the life of medieval society. Particular attention is paid to the human dimension of war. The author notes the characteristics of war in the Middle Ages. The article highlighted the distinctive features of the war
Vladimir Kuzmich Karnaukh
doaj
Travel, leisure, boredom and the Middle Ages
Tabula, 2016 The subject of this analysis deals with the concepts of travel, leisure and boredom, with emphasis on the medieval period. What was travel to a man of the Middle Ages, and was there any place in his life for leisure, and especially boredom?
Maja Jović
doaj +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source