Results 31 to 40 of about 128,537,122 (247)

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

open access: yesFEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard   +12 more
wiley   +1 more source

PENGGUNAAN SIMULASI MONTE CARLO DALAM ESTIMASI VALUE AT RISK (VaR) PORTOFOLIO YANG DIBENTUK DARI INDEKS HARGA SAHAM MULTINASIONAL

open access: yesE-Jurnal Matematika, 2022
Investment is buying an asset that is expected in the future can be resold and get a high profit value. There are two factors that must be considered when you want to invest in stocks, namely the rate of return on stocks and risk factors.
NABILA NUR JANNAH   +2 more
doaj   +1 more source

Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA

open access: yesFEBS Open Bio, EarlyView.
PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro   +1 more
wiley   +1 more source

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

open access: yesFEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty   +13 more
wiley   +1 more source

A comparative study between Classical Numerical Methods and Monte Carlo Methods [PDF]

open access: yesالمجلة العراقية للعلوم الاحصائية, 2008
Recently, there is a great interest in the methods of Monte Carlo used for the treatment of different technical and scientific issues. This research deals with using the Monte Carlo methods in numerical integration by making a general comparison between
doaj   +1 more source

Understanding Further the Phenotypic Spectrum of Central Nervous System Inflammatory Demyelinating Disorders Using Unsupervised Clustering

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Central nervous system (CNS) inflammatory demyelinating syndromes, including multiple sclerosis (MS), aquaporin‐4 antibody–positive neuromyelitis optica spectrum disorder (AQP4 + NMOSD), and myelin oligodendrocyte glycoprotein (MOG) antibody–associated disease (MOGAD), occasionally overlap.
Bade Gulec   +6 more
wiley   +1 more source

An Efficient Anti-Optimization Approach for Uncertainty Analysis in Composite Laminates

open access: yesMaterials Research, 2021
This work presents an efficient approach to quantify uncertainties in composite laminates using the interval analysis, anti-optimization technique, and the α-cut procedure.
Pedro Bührer Santana   +2 more
doaj   +1 more source

Efficient Monte Carlo filtering for discretely observed jumping processes [PDF]

open access: yes, 2007
This paper addresses a tracking problem in which the unobserved process is characterised by a collection of random jump times and associated random parameters.
Simon Godsill   +5 more
core   +1 more source

Risk of Non‐Arteritic Anterior Ischemic Optic Neuropathy in Idiopathic Intracranial Hypertension Patients Treated with GLP‐1 Receptor Agonists

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Introduction Glucagon‐like peptide‐1 receptor agonists (GLP‐1 RAs) have demonstrated significant weight‐reducing effects and may offer benefits in idiopathic intracranial hypertension (IIH); however, recent concerns about the risk of non‐arteritic anterior ischemic optic neuropathy (NAION) have emerged.
Faisal A. Al‐Harbi   +9 more
wiley   +1 more source

A top-down iteration algorithm for Monte Carlo method for probability estimation of a fault tree with circular logic

open access: yesNuclear Engineering and Technology, 2018
Calculating minimal cut sets is a typical quantification method used to evaluate the top event probability for a fault tree. If minimal cut sets cannot be calculated or if the accuracy of the quantification result is in doubt, the Monte Carlo method can ...
Sang Hoon Han
doaj   +1 more source

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