Results 101 to 110 of about 137,617,223 (311)
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
A Qualitative Study on Development of Enriching Performance Management System at a Pharma-Company [PDF]
, 2018 This case study aimed to develop a sample of enriching the performance management system using qualitative method. The job post of Import Executive in a pharma company has been selected as a sample.
Hanif, Muhammad A.; Institute of Business Management, Karachi +2 more
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Molecular Oncology, EarlyView.RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
New Jersey Floodplain News: Issue 4
, 2008 New Jersey Association for Floodplain Management (NJAFM) is dedicated to reducing loss of life and property damage resulting from floods and promoting sound floodplain management at all levels of government. This issue of NJAFM's newsletter features the
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Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
New Jersey Coastal Management Program: Assessment and Enhancement Strategy FY 2006-2010
, 2006 This document is the 2006 assessment and enhancement strategy for New Jersey's Coastal Management Program. New Jersey is required by the Federal Coastal Zone Management Act to assess its Coastal Management Program every five years and provide a strategy ...
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Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Applied Computer Systems, 2014 Nowadays software configuration management process is not only dilemma which system should be used for version control or how to merge changes from one source code branch to other.
Bartusevics Arturs +2 more
doaj +1 more source
, 1978 An inventory of New Jersey lakes in the New Jersey Department of Environmental Protection Lakes Management Program. The lakes are organized alphabetically by county and information is included for each on ownership, municipality, watershed, and prime ...
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