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Promising New Approaches to the Management of Obesity

Drugs, 2000
The pathophysiology of obesity is complex with many different pathways involved. A better understanding of these weight-regulating mechanisms has lead to the identification of new targets for anti-obesity agents. Most attention has been given to the centrally acting neuropeptides regulating food intake.
Mertens, I., Van Gaal, Luc
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New approaches to the management of fibroids

Current Opinion in Obstetrics and Gynecology, 1991
It is clear that gonadotropin-releasing hormone agonists have potential as a new therapeutic approach in the treatment of fibroids. They are effective in decreasing the size of most fibroids but, on ceasing treatment, regrowth does occur. Because of their effect on calcium homeostasis, long-term unopposed use of these agonists is not recommended ...
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Self-Organising News Management: the Molecules of Knowledge Approach

2012 IEEE Sixth International Conference on Self-Adaptive and Self-Organizing Systems Workshops, 2012
Nowadays, news management systems present new critical challenges in the knowledge management process: the ever-increasing amount of information to handle, its heterogeneity in structure, and the pace at which it is made available are just a few to mention. Features such as autonomy and self-organisation are essential to face challenges of such a sort:
MARIANI, STEFANO, OMICINI, ANDREA
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New Approaches to the Management of COPD

Chest, 2000
Airflow limitation in COPD is a result partially of bronchospasm, but it is also caused by a reduction in airway caliber, the number of small airways, airway collapse because of loss of connective tissue support, excess mucus in the airways, and edema of the airway wall.
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NEW APPROACHES TO THE MANAGEMENT OF FIBROIDS

Obstetrics and Gynecology Clinics of North America, 2000
New and innovative treatments are available for the control of uterine leiomyomata, each with advantages and disadvantages. Most of these techniques have few data to support their use; they are generally poorly studied, with brief follow-up. Not much is known regarding risks, costs, and comparative value.
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New approaches for the strategic management of technology

Technology in Society, 1985
Technology is an increasingly important element in the business of many large corporations; its impact, however, is complex and often difficult to integrate into the strategic management process. Thisdifficulty arises in part because technical advances—in addition to providing new ways to implement existingbusiness strategy — often bring about the need
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New Therapeutic Approaches to the Management of Rheumatoid Arthritis

BioDrugs, 2001
Rheumatoid arthritis (RA) is a common disease that affects up to 1% of the population, and causes significant morbidity and early mortality. The aetiology of RA is unknown; however, in the last 10 to 15 years significant advances in molecular technology have provided a greater understanding of the pathogenesis of the disease.
L B, Hughes, L W, Moreland
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New approaches for the management of cervical cancer

Gynecologic Oncology, 2003
Since the introduction of the Pap test by George Papanicolaou, the incidence of cervical cancer has fallen and mortality has decreased, in parallel with effective treatment of the precancerous and in situ stages of the disease. However, women who are not diagnosed through screening usually present with advanced disease.
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New Approaches in the Management of Inhibitor Patients

Acta Haematologica, 2006
The most serious current complication of factor replacement therapy for hemophilia patients is the development of neutralizing antibodies to the factor termed inhibitors. Patients with high-titer inhibitors frequently develop serious bleeding complications which do not respond to standard factor replacement therapy. Therefore, they must be treated with
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