Results 71 to 80 of about 147,691,590 (309)

New Approach in the Management of Vertical Root Fracture with the Help of Biodentine and CBCT

open access: yesCase Reports in Dentistry, 2020
Introduction. Vertical root fracture is a big challenge to dentists for its diagnosis and treatment. As the tooth presents poor prognosis, the most common treatment modality is extraction.
H. C. Baranwal   +5 more
doaj   +1 more source

Understanding the very nature of Project Management : a praxiological approach [PDF]

open access: yes, 2005
Foreword: In this paper I call upon a praxiological approach. Praxeology (early alteration of praxiology) is the study of human action and conduct. The name praxeology/praxiologyakes is root in praxis, Medieval Latin, from Greek, doing, action, from ...
Bredillet, Christophe
core   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

An Examination of the New Public Management Approach from the Perspective of Bureaucratic Ethics

open access: yesİnönü Üniversitesi Uluslararası Sosyal Bilimler Dergisi
This study aims to establish a relationship and make a comparison between Max Weber's concept of bureaucracy and bureaucratic ethics and the New Public Management (NPM) approach.
Hasan Yılmaz
doaj   +1 more source

New pharmacological approaches for obesity management [PDF]

open access: yesNature Reviews Endocrinology, 2013
Obesity, which results from an imbalance between calorie intake and expenditure, now affects over 500 million individuals worldwide. Lifestyle and behavioural interventions aimed at reducing calorie intake and/or increasing energy expenditure have limited long-term effectiveness due to complex and persistent hormonal, metabolic and neurochemical ...
Rueda-Clausen, Christian F.   +2 more
openaire   +3 more sources

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Management: history, development, classical direction and basic principles of the system approach [PDF]

open access: yes, 2015
Sunt analizate perioadele istorice de apariţie şi dezvoltare a managementului, precum şi direcţiile clasice şi şcolile ştiinţifice din domeniu. Autorul analizează modelele noilor abordări manageriale.The analysis of the historical time of the origin and ...
Чебан, В.И.
core   +1 more source

Biodiversity Data Management Project: Extending the Boundaries of Information Management in Collaboration with Life Scientists at the University of Otago [PDF]

open access: yes, 2009
Original version of article with links updated.The Otago Biodiversity Data Management Project investigated the feasibility of managing, curating and sharing University of Otago biodiversity research data. This article discusses how the Project came about
Elliot, Gillian
core  

Emerging experimental and computational methods for studying redox‐regulated structural transitions

open access: yesFEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass   +2 more
wiley   +1 more source

RNA‐related functions of BRCA2 in transcription, replication, and genome stability

open access: yesFEBS Letters, EarlyView.
Beyond its role in homologous recombination, BRCA2 regulates R‐loop homeostasis, DNA–RNA hybrid resolution, RNA polymerase II dynamics, and transcriptional activation. Disruption of any of these functions can contribute to genome instability, inflammatory signaling, and tumorigenesis. BRCA2 is a central tumor suppressor protein best known for its roles
Lucia Alvaro‐Aranda   +2 more
wiley   +1 more source

Home - About - Disclaimer - Privacy