Results 91 to 100 of about 147,691,590 (309)

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Sentinel Lymph Node Biopsy : A new approach in the management of head and neck cancers

Sultan Qaboos University Medical Journal, 2017
Cervical lymph node metastasis affects the prognosis and overall survival rate of and therapeutic planning for patients with head and neck squamous cell carcinomas (HNSCCs).
Deepti Sharma, George Koshy, Sonal Grover   +2 more
doaj   +1 more source

Priapism — A New Approach to Management [PDF]

Proceedings of the Royal Society of Medicine, 1968
W R, Bell, W R, Pitney
openaire   +2 more sources

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

A new approach in Business Process Management [PDF]

The new wave of BPM (Business Process Management) is not Business Process Reenginering, enterprise application integration, workflow management or another packaged application – it's the synthesis and extension of all these technologies and techniques ...
Hurbean, Luminita
core  

Cancer‐associated mutations in endometriosis reframe a benign disease through molecular oncology

Molecular Oncology, EarlyView.
This review aims to comprehensively analyse cancer‐associated somatic mutations (CAMs) present in endometriotic lesions, emphasizing their biological roles, spatial distribution and implications for translational applications in medicine. By contextualizing a benign state within a genomic framework, this analysis seeks to establish its value as a ...
Clarissa Mujacic, Maria Concetta Vitale, Rita Siino, Emilia Di Giovanni, Carla Ferrante Bannera, Enrico Di Marco, Andrea Gottardo, Tancredi Didier Bazan Russo, Nadia Barraco, Alessandro Perez, Valerio Gristina, Antonio Galvano, Giuseppe Badalamenti, Antonio Russo, Viviana Bazan, Lorena Incorvaia   +15 more
wiley   +1 more source

Identifying critical success factors in Key Account Management, along with characteristics of Key Account Managers, in order to develop a new model and approach to implementation

, 2016
This research was a developmental paper ‘Identifying critical success factors in key account management, along with characteristics of key account managers, in order to develop a new model and approach to ...
Veasey, C.
core  

Viable service systems and decision making in service management [PDF]

, 2012
This paper addresses decision making in the management of complex service systems, highlighting the contribution of the viable systems approach as an interpretative and governance methodology based on systems thinking.
Ng Irene C. L., M. Saviano, Polese, Francesco, Di Nauta, Primiano, F. Polese, Saviano, Marialuisa, Barile S., Barile, Sergio, I. Ng, Ng, Irene C. L., Badinelli, Ralph, Di Nauta P., Badinelli R., Badinelli, Ralph D., R. Badinelli, P. Di Nauta, Nauta, Primiano Di   +16 more
core   +1 more source

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

Molecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach, Gizem Abaci, Tom Huberty, Axel Lechner, Lukas Käsmann, Jens Ricke, Sophia Stöcklein, Martin Canis, Philipp Baumeister, Marianna Alunni‐Fabbroni   +9 more
wiley   +1 more source

Genetic structure and historic demography of endangered unarmoured threespine stickleback at southern latitudes signals a potential new management approach. [PDF]

Mol Ecol, 2022
Turba R, Richmond JQ, Fitz-Gibbon S, Morselli M, Fisher RN, Swift CC, Ruiz-Campos G, Backlin AR, Dellith C, Jacobs DK.   +9 more
europepmc   +1 more source