Results 41 to 50 of about 826,987 (211)

Biophysical approaches for studying viral entry

open access: yesFEBS Letters, EarlyView.
Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley   +1 more source

Blood lipid spectrum in hypertensive patients and normotensive subjects living in the Khanty-Mansiysk region

open access: yesТерапевтический архив, 2009
Aim. To evaluate basic parameters of lipid metabolism in patients with arterial hypertension (AH) stage I and II and normotensive subjects living in the far North of the Russian Federation (Khanty-Mansiysk Autonomic Region, Nyagan). Material and methods.
Irina Mikhaylovna Mikhaylova   +9 more
doaj  

EPISTOLARY SOURCES IN BIOGRAPHICAL RESEARCH: “CAUCASIAN LETTERS” BY A.P.ERMOLOV

open access: yesГуманитарные и юридические исследования, 2021
The article deals with potentials of sources of personal origin, particularly, epistolary heritage for doing biographical research. The author studies “Caucasian Letters” by A.P.Ermolov - a person whose name symbolizes a particular era in the history of ...
M. Kolesnikova
doaj  

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

open access: yesFEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai   +4 more
wiley   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Current medico-ecological aspects of internal medicines in urbanic North

open access: yesТерапевтический архив, 2003
Aim. To define a complex action of extreme climatic and harmful environmental factors of present-day northern industrial city on the course of chronic visceral diseases. Material and methods.
V A Karpin
doaj  

Large-scale, cross-flow based isolation of highly pure and endocytosis-competent extracellular vesicles

open access: yesJournal of Extracellular Vesicles, 2018
Isolation of extracellular vesicles (EVs) from cell culture supernatant or plasma can be accomplished in a variety of ways. Common measures to quantify relative success are: concentration of the EVs, purity from non-EVs associated protein, size ...
Ryan P. McNamara   +6 more
doaj   +1 more source

The Genus Tithymalus Gaertn. in Northern Caucasus

open access: yesЮг России: экология, развитие, 2015
In article data on specific of sort Tithymalus in the North Caucasus are resulted. Geographical diffusion of its kinds on flora areas is analyzed.
A. A. Terekbaev, A. A. Teimurov
doaj   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

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