Results 111 to 120 of about 38,795,041 (290)

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira   +14 more
wiley   +1 more source

On South African Violence Through Giorgio Agamben’s Biopolitical Framework: A Comparative Study Of J.M. Coetzee’s Disgrace And Z. Mda’s Ways Of Dying

open access: yesStudia Anglica Posnaniensia, 2014
In this article I argue that the developments of countries going through transition from authoritarian to democratic rule are always stamped by numerous references to formerly sanctioned and fully operational institutionalized violence.
Bartnik Ryszard
doaj   +1 more source

The complexity of general-valued CSPs seen from the other side

open access: yes, 2018
The constraint satisfaction problem (CSP) is concerned with homomorphisms between two structures. For CSPs with restricted left-hand side structures, the results of Dalmau, Kolaitis, and Vardi [CP'02], Grohe [FOCS'03/JACM'07], and Atserias, Bulatov, and ...
Carbonnel, Clement   +2 more
core   +2 more sources

Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer

open access: yesMolecular Oncology, EarlyView.
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian   +10 more
wiley   +1 more source

Icebergs in the Clouds: the Other Risks of Cloud Computing [PDF]

open access: yes, 2012
Cloud computing is appealing from management and efficiency perspectives, but brings risks both known and unknown. Well-known and hotly-debated information security risks, due to software vulnerabilities, insider attacks, and side-channels for example ...
Ford, Bryan
core   +1 more source

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

open access: yesMolecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath   +13 more
wiley   +1 more source

Edukacja/Migracja, czyli zamierzony rym

open access: yesPostscriptum Polonistyczne, 2020
The article aims at presenting a critical review of the book Edukacja. Migracja. Edukacja międzykulturowa w kontekście kryzysu migracyjnego z perspektywy krajów V4 [Education. Migration.
Małgorzata Wójcik-Dudek
doaj  

Gut microbiota diversity is prognostic in metastatic hormone receptor‐positive breast cancer patients receiving chemotherapy and immunotherapy

open access: yesMolecular Oncology, EarlyView.
In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern   +7 more
wiley   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

open access: yesMolecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici   +8 more
wiley   +1 more source

Silencing the Other in ‘The Artist’ (2006) by Maggie Gee

open access: yesФилологический класс, 2020
The study proposes an interpretation of Maggie Gee’s short story The Artist (2006) through Bakhtinian perspective, which enables its reading both as a piece of social criticism and as a mediation about the true artist’s capacity for empathy and ...
doaj   +1 more source

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