Results 81 to 90 of about 38,795,041 (290)
Time after time – circadian clocks through the lens of oscillator theory
FEBS Letters, EarlyView.Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
Sampling the Fermi statistics and other conditional product measures [PDF]
, 2011 Through a Metropolis-like algorithm with single step computational cost of order one, we build a Markov chain that relaxes to the canonical Fermi statistics for k non-interacting particles among m energy levels.
Gaudilliere, Alexandre, Reygner, Julien
core +3 more sources
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
FEBS Letters, EarlyView.Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
Other Exotic Scenarios at the LHC [PDF]
, 2006 The considerable center-of-mass energy and luminosity provided by the Large Hadron Collider (LHC) will ensure a discovery reach for new particles which extends well into the multi-TeV region.
Benslama, Kamal
core +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
The Other Side of Peirce's Phaneroscopy [PDF]
, 2019 Research on Peirce’s phaneroscopy has been done with and through the paradigm or the conceptual schema of “Being” — what has been critiqued by post-structuralist philosophers as the metaphysics of Being.
Ioannidis, Iraklis
core
FEBS Letters, EarlyView.Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman +2 more
wiley +1 more source
, 2002 A meditation on how psychoanalysis, as the "only real discipline of the excessive," has an indispensable contribution to make in fathoming the "causeless hatred" of racism and bigotry that continues to plague the human species. Frosh cites both Lacan and
Frosh, Stephen
core +1 more source
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
‘A Pause for Po-Ethics’: Seamus Heaney and the Ethics of Aesthetics
Humanities, 2019 In this paper, I examine the connections between ethics and aesthetics in the writing of Seamus Heaney. Looking at Heaney’s neologism of ‘po-ethics’, I move through his poetry and especially his translation of Sophocles’ ...
Eugene O’Brien
doaj +1 more source