Results 81 to 90 of about 39,331,486 (304)

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Religious Fanaticism or Faith Tradition: the Entangled Soul of an Immigrant [PDF]

University of Bucharest Review. Literary and Cultural Studies Series, 2015
The paper discusses two contemporary literary works, i.e. Hanif Kureishis’s short story My Son the Fanatic and Elif Shafak’s novel Honour. The discussion will concern the adaptation/rejection of religious values by the immigrant community in a new ...
Dorota Owczarek
doaj  

Autoimmunity to Tropomyosin-Specific Peptides Induced by Mycobacterium leprae in Leprosy Patients: Identification of Mimicking Proteins

Frontiers in Immunology, 2018
BackgroundIt has been shown earlier that there is a rise in the levels of autoantibodies and T cell response to cytoskeletal proteins in leprosy. Our group recently demonstrated a rise in both T and B cell responses to keratin and myelin basic protein in
Itu Singh, Asha Ram Yadav, Keshar Kunja Mohanty, Kiran Katoch, Prashant Sharma, Vinay Kumar Pathak, Deepa Bisht, Umesh D. Gupta, Utpal Sengupta   +8 more
doaj   +1 more source

AAA+ protein unfoldases—the Moirai of the proteome

FEBS Letters, EarlyView.
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley   +1 more source

The Kuiper Belt and Other Debris Disks

, 2008
We discuss the current knowledge of the Solar system, focusing on bodies in the outer regions, on the information they provide concerning Solar system formation, and on the possible relationships that may exist between our system and the debris disks of ...
A. Bar-Nun, A. Delsanti, A. Higuchi, A. Morbidelli, A. Morbidelli, A. Moro-Martín, A. Moro-Martín, A.C. Boley, A.P. Boss, A.P. Boss, A.P. Boss, A.W. Harris, B. Gladman, B. Zuckerman, C. Alcock, C. Beichman, C. Leinert, C.A. Trujillo, C.M. Lisse, C.R. Chapman, D. Babich, D. Jewitt, D. Jewitt, D. Jewitt, D. Jewitt, D. Jewitt, D. Jewitt, D.A. Gurnett, D.C. Hines, D.C. Jewitt, D.C. Jewitt, D.C. Jewitt, D.E. Backman, D.E. Brownlee, D.E. Trilling, D.E. Trilling, D.R. Davis, E. Grün, E.F. Young, E.J. Gaidos, F. Paresce, F.C. Adams, G. Bryden, G. Marcy, G. Schneider, G.H. Rieke, G.J. Melnick, H.A. Zook, H.F. Levison, H.F. Levison, H.F. Levison, H.H. Hsieh, I. Song, J. Luu, J. Luu, J. Luu, J. Weingartner, J.-C. Liou, J.A. Burns, J.A. Fernández, J.A. Fernández, J.D. Anderson, J.H. Debes, J.H. Oort, J.L. Elliot, J.M. Hahn, J.S. Greaves, K. Grogan, K. Willacy, K.E.S. Ford, K.R. Stapelfeldt, K.Y.L. Su, K.Y.L. Su, L.A. Hillenbrand, L.M. Trafton, M. Duncan, M. Jura, M. Jura, M.C. Liu, M.C. Liu, M.C. Wyatt, M.C. Wyatt, M.E. Brown, M.E. Brown, M.J. Duncan, M.J. Holman, M.J. Kuchner, M.R. Meyer, M.V. Sykes, M.W. Buie, N. Gorlova, N. Gorlova, N. Ouellette, N. Peixinho, N. Siegler, P. Farinella, P. Kalas, P. Kalas, P. Lacerda, P. Lacerda, P. Lacerda, P. Lacerda, P. Thébault, P.J. Francis, R. Gomes, R. Malhotra, R.G. Strom, R.S. Gomes, S. Ida, S. Mostefaoui, S. Takahashi, S. Yamamoto, S.A. Stern, S.C. Tegler, S.F. Dermott, S.F. Dermott, S.J. Kenyon, S.R. Heap, S.S. Sheppard, S.S. Sheppard, S.S. Sheppard, S.S. Sheppard, T. Guillot, T. Lee, V. Catullo, W.F. Bottke, W.J. Baggaley, W.K.M. Rice, W.S. Holland, W.S. Holland, W.S. Holland, W.T. Reach, y Barrado, Y.R. Fernàndez   +133 more
core   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

FEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

The Image of History as a Playground [PDF]

Annals of Philosophy, Social and Human Disciplines, 2013
This study analyzes the problem of history seen as a playground between two different worlds: Eastern and Western Europe. The article draws attention to the relation between the two European regions from the cultural and historical point of view. The two
Carmen DOMINTE
doaj  

‘A Pause for Po-Ethics’: Seamus Heaney and the Ethics of Aesthetics

Humanities, 2019
In this paper, I examine the connections between ethics and aesthetics in the writing of Seamus Heaney. Looking at Heaney’s neologism of ‘po-ethics’, I move through his poetry and especially his translation of Sophocles’ ...
Eugene O’Brien
doaj   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source

Oryantalizm ve “Öteki” Algısı

Skad, 2015
Varlığı Doğu ile Batının varlığı kadar eskiye dayandırılabilecek Oryantalizm disiplini temelde Doğu ve Batı dünyaları arasında hüküm sürdüğü düşünülen bir hakimiyet mücadelesi ve çatışma üzerine kurulmuştur.
Meryem Köse, Meryem Küçük
doaj