Results 31 to 40 of about 1,223,834 (250)

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

Molecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués, Aracele Martinez‐Mendez, John Crown, Alex Eustace   +3 more
wiley   +1 more source

The perfect man in Islamic philosophy, reality or illusion [PDF]

Kom: Časopis za Religijske Nauke, 2017
In the works of Islamic philosophers, the position of the ideal head of the ideal society was occupied by the divine prophet who, according to their description, possessed all the virtues of a human being can possibly have. Unlike an ideal society which,
Halilović Tehran
doaj  

Pascal Principle for Diffusion-Controlled Trapping Reactions

, 2003
"All misfortune of man comes from the fact that he does not stay peacefully in his room", has once asserted Blaise Pascal. In the present paper we evoke this statement as the "Pascal principle" in regard to the problem of survival of an "A" particle ...
A. Blumen, A. Szabo, A.A. Ovchinnikov, A.J. Bray, A.M. Berezhkovskii, B.Ya. Balagurov, E. Montroll, G. Oshanin, G. Oshanin, M. Bramson, M. Coppey, M. Moreau, M. Tachiya, M.D. Donsker, O. Bénichou, O. Bénichou, P. Grassberger, S. Redner, S.F. Burlatsky, S.F. Burlatsky, S.R. Renn, T.C. Lubensky, Th.M. Nieuwenhuizen   +22 more
core   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Victor Tufescu or the Perfect Elegance of Man and Spirit [PDF]

Amfiteatru Economic
In the 1950s and 1960s, the Department of Economic Geography at the Bucharest University of Economic Studies (BUES, in Romanian known as “ASE”) was part of the Faculty of Commerce (now the Faculty of Business and Tourism).
Silviu Neguţ
doaj   +1 more source

A subtitling analysis on maxim flouts in a cinderella story and the perfect man movies from english into indonesian [PDF]

, 2014
The study aims to describe (1) maxim flouts found in A Cinderella Story and The Perfect Man Movies from English to Indonesian, (2) the accuracy of maxim flouts translation in A Cinderella Story and The Perfect Man Movies from English to Indonesian, (3)
, Agus Wijayanto, Ph.D, -, Dr. Anam Sutopo, M.Hum, Maslahah, Frida Alfani   +2 more
core  

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

Molecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris, Vasiliki Siozopoulou, Léon C van Kempen, Anne Sieben, Ella Roelant, Stig Hellemans, Elyne Backx, Laure Sorber, Koen De Winne, Senada Koljenović, Karen Zwaenepoel   +10 more
wiley   +1 more source

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

Molecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

A Coherent Account of the Structure of Mysticism [PDF]

تاریخ فلسفه اسلامی, 2022
Knowing the Divine Names as the truths that have appeared in the world and the divine manifestations through which the world is adorned and determined, is the knowledge of the Sharia from the side that the mysticism of intuition is bound to the Sharia ...
Hossein Shekarabi
doaj  

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source